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IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Gene Name: IMP (inosine 5'-monophosphate) dehydrogenase 2
Synonyms: IMPDH2, IMP dehydrogenase 2, IMP oxireductase 2, IMPD2, IMPDH-II, Dna binding protein rfx2, IMPD 2, IMPDH 2
Target Sequences: NM_000884 NP_000875.2 P12268

☰ Filters
Antibodies (46)
Proteins (9)
ELISA Kits (4)
Over-Expression Lysate (3)
Primary (46)
Recombinant (6)
Sandwich (4)
IMPDH2 (59)
Human (49)
Mouse (17)
Rat (13)
Amphibian (1)
Bat (6)
Bovine (7)
Chicken (1)
Chimpanzee (6)
Dog (7)
Gibbon (6)
Guinea pig (7)
Hamster (6)
Hamster-Chinese (1)
Horse (7)
Monkey (6)
Opossum (1)
Pig (7)
Primate (1)
Rabbit (4)
Xenopus (3)
Zebrafish (3)
IHC (16)
IHC-P (4)
WB (45)
Flo (1)
ELISA (13)
ICC (1)
IF (4)
IP (2)
Peptide-ELISA (2)
RNAi (1)
rabbit (42)
mouse (3)
goat (1)
IgG (27)
IgG1 (1)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (44)
1E12-B6 (1)
OTI2F10 (1)
96-Well Strip Plate (4)
APC (1)
APC Conjugated (2)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Unconjugated (22)
aa226-514 (8)
C-Terminus (4)
N-Terminus (4)
aa167-178 (1)
aa180-210 (1)
aa215-514 (1)
aa221-248 (1)
No (59)
Cell Culture Supernatants (1)
Cell Lysates (1)
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Serum (3)
Tissue Homogenates (4)
6His, N-terminus (2)
GST (1)
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His (1)
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Human (8)
293T Cells (1)
E. coli (4)
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Purified (3)
IMPDH2 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
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E. coli
6His, N-terminus
58 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
IMPDH2 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer using antibody at dilution of 1:100.
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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IMPDH2 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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IMPDH2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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IMPDH2 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
IMPDH2 Antibody - Western Blot analysis of IMPDH2 expression in transfected 293T cell line by IMPDH2 monoclonal antibody (M01), clone 1E12-B6.Lane 1: IMPDH2 transfected lysate(55.8 KDa).Lane 2: Non-transfected lysate.
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IMPDH2 Mouse anti-Human Monoclonal (1E12-B6) Antibody
Human
ELISA, IP, RNAi, WB
Unconjugated
100 µg/$423
IMPDH2 Antibody - IMPDH2 Antibody IHC of formalin-fixed and paraffin-embedded human Lung carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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IMPDH2 Rabbit anti-Human Polyclonal (aa180-210) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
IMPDH2 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer using IMPDH2 Antibody at dilution of 1:100
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
IMPDH2 Antibody - Western blot of Peptidyl-prolyl cis-trans isomerase FKBP1A antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 56.5 kDa. Observed band size: 56.5 kDa Additional bands at: 50 kDa, 70 kDa; We are unsure as to the identity of these extra bands.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IMPDH2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
IMPDH2 Antibody - Western blot of Peptidyl-prolyl cis-trans isomerase FKBP1A antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 56.5 kDa. Observed band size: 56.5 kDa Additional bands at: 50 kDa, 70 kDa; We are unsure as to the identity of these extra bands.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IMPDH2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
IMPDH2 Antibody - Western blot of Peptidyl-prolyl cis-trans isomerase FKBP1A antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 56.5 kDa. Observed band size: 56.5 kDa Additional bands at: 50 kDa, 70 kDa; We are unsure as to the identity of these extra bands.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IMPDH2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
IMPDH2 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
IMPDH2 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using IMPDH2 Polyclonal Antibody at dilution of 1:60.
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IMPDH2 Antibody - Immunofluorescence analysis of HeLa cells.
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IMPDH2 Antibody - Immunofluorescent analysis of IMPDH2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
IMPDH2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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IMPDH2 Rabbit anti-Human Polyclonal (aa215-514) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
IMPDH2 Antibody - Immunohistochemistry-Paraffin: IMPDH2 Antibody - Analysis of IMPDH in human stomach tissue using IMPDH antibody at 5 ug/ml.
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IMPDH2 Rabbit anti-Human Polyclonal (aa221-248) Antibody
Amphibian, Chicken, Bovine, Rat, Opossum, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Hamster-Chinese, Primate, Human
IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
IMPDH2 Antibody - 1:100 staining mouse heart tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
IMPDH2 Antibody - IMPDH2 antibody (1 ug/ml) staining of Human Skeletal Muscle lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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IMPDH2 Goat anti-Human Polyclonal (aa167-178) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
IMPDH2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY IMPDH2. (Right lane) cDNA for 48 hrs and lysed
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IMPDH2 Mouse anti-Human Monoclonal (OTI2F10) Antibody
Human
WB
Unconjugated
100 µl/$434
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IMPDH2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
IMPDH2 Antibody - IMPDH2 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IMPDH2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 59 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).