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IMPACT

impact RWD domain protein

Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis By similarity. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis By similarity. Through its action on GCN2, may also facilitate neuritogenesis.

Gene Name: impact RWD domain protein
Synonyms: IMPACT, Impact homolog (mouse), Imprinted and ancient, Impact RWD domain protein, Protein IMPACT, RWDD5
Target Sequences: NM_018439 NP_060909.1 Q9P2X3

☰ Filters
Antibodies (13)
Proteins (5)
Over-Expression Lysate (2)
Primary (13)
Recombinant (3)
IMPACT (18)
Human (13)
Rat (1)
WB (9)
ELISA (10)
IP (1)
rabbit (12)
mouse (1)
IgG (12)
polyclonal pc (13)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (5)
aa1-30 (7)
aa270-320 (1)
No (18)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
Select
IMPACT Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
IMPACT Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
IMPACT Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
IMPACT Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
IMPACT Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
IMPACT Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
IMPACT Rabbit anti-Human Polyclonal (aa270-320) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
IMPACT Antibody - Immunohistochemistry of paraffin-embedded human endometrial cancer using IMPACT Antibody at dilution of 1:100
Select
IMPACT Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
IMPACT Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
IMPACT Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
IMPACT Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
IMPACT Antibody - IMPACT Antibody western blot of HeLa cell line lysates (35 ug/lane). The IMPACT antibody detected the IMPACT protein (arrow).
Select
IMPACT Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
IMPACT Mouse anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
50 µg/$705
IMPACT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.3 kDa
20 µg/$150
IMPACT Protein - Purified recombinant protein IMPACT was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
36.3 kDa
20 µg/$1,107
IMPACT Protein - 12.5% SDS-PAGE of human IMPACT stained with Coomassie Blue
Select
Wheat Germ Extract
GST
60.83 kDa
10 µg/$479; 25 µg/$670
IMPACT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.3 kDa
100 µg/$494
IMPACT Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-18 of 18 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).