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IL8 / Interleukin 8

interleukin 8

Interleukin 8 (IL8), a member of the CXC chemokine family. This chemokine, is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.

Gene Name: interleukin 8
Family/Subfamily: Intercrine , Intercrine alpha
Synonyms: CXCL8, 3-10C, AMCF-I, B-ENAP, C-X-C motif chemokine 8, GCP-1, IL-8, IL8, Interleukin-8, K60, LECT, GCP1, LUCT, NAF, NAP1, Neutrophil-activating factor, Interleukin 8, Protein 3-10C, MDNCF, TSG-1, Emoctakin, LYNAP, MONAP, NAP-1, SCYB8, T-cell chemotactic factor
Target Sequences: NM_000584 NP_000575.1 P10145

Publications (6)

1
Unique early gene expression patterns in human adult-to-adult living donor liver grafts compared to deceased donor grafts. de Jonge J, Kurian S, Shaked A, Reddy KR, Hancock W, Salomon DR, Olthoff KM. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2009 9:758-72. (IHC) [PubMed:19353763] [PMC:PMC2734955]
2
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human) [Full Text Article] [PubMed:25870011] [PMC:PMC4623112] Related Antibodies: LS-C104558.
3
Expression and secretion of the pro-inflammatory cytokine IL-8 is increased in colorectal cancer cells following the knockdown of non-erythroid spectrin aII. Anne Ackermann, Barbara Lafferton, Guido Plotz, Stefan Zeuzem, Angela Brieger. International journal of oncology. 2020 June;56:1551-1564. [Full Text Article] [PubMed:32236629] Related Antibodies: LS-C663556.
4
Free fatty acids promote degranulation of azurophil granules in neutrophils by inducing production of NADPH oxidase-derived reactive oxygen species in cows with subclinical ketosis. Yuxiang Song, Shang Jiang, Congyi Li, Juan J Loor, Qianming Jiang, Yuchen Yang, Xiancheng Feng, Siyuan Liu, Jiyuan He, Kexin Wang, Yunfei Li, Cai Zhang, Xiliang Du, Zhe Wang, Xinwei Li, Guowen Liu. Journal of dairy science. 2022 March;105:2473-2486. [Full Text Article] [PubMed:34998570]
5
LncRNA H19 aggravates TNF-a-induced inflammatory injury via TAK1 pathway in MH7A cells. Jialiang Yang, Yixuan Li, Lili Wang, Zhenchun Zhang, Zunzhong Li, Qian Jia. BioFactors (Oxford, England). 2020 September;46:813-820. [Full Text Article] [PubMed:32525617] Related Antibodies: LS-C104558.
6
Plexin-B1 activates NF- kappa B and IL-8 to promote a pro-angiogenic response in endothelial cells. Yang YH, Zhou H, Binmadi NO, Proia P, Basile JR. PloS one. 2011 6:e25826. [Full Text Article] [PubMed:22028792] [PMC:PMC3196529] Related Antibodies: LS-C8020.
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IL8 / Interleukin 8 Antibody - Western Blot (non-reducing) of IL-8 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL8 / Interleukin 8 Antibody - Anti-IL-8 antibody IHC of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal (5D8) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal (I8-60) Antibody
Human
ELISA, Neut, WB
Unconjugated
100 µg/$426; 500 µg/$740
IL8 / Interleukin 8 Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma reacted with IL8 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal (aa72-99) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Neut, WB
Unconjugated
500 µg/$688
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-Fr
Unconjugated
100 µg/$551; 500 µg/$1,375
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
IL8 / Interleukin 8 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$587
IL8 / Interleukin 8 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$636
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$741
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
IL8 / Interleukin 8 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
IL8 / Interleukin 8 ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
IL8 / Interleukin 8 Antibody - Western Blot; Sample: Recombinant IL8, Human.
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal (C4) Antibody
Human
WB
Unconjugated
100 µl/$292; 200 µl/$327; 500 µl/$443; 1 ml/$501; 2 ml/$626; 5 ml/$1,072
IL8 / Interleukin 8 Antibody - 1/100 staining human kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary antibody.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL8 / Interleukin 8 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal (aa77-95) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
IL8 / Interleukin 8 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal (aa77-95) (Magnetic beads) Antibody
Human
IP
Magnetic beads Conjugated
100 µg/$399
IL8 / Interleukin 8 Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC-P
Unconjugated
50 µg/$460
IL8 / Interleukin 8 Antibody - Anti-Human IL-8 (CXCL8) Western Blot Unreduced
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$326
IL8 / Interleukin 8 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$719
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IL8 / Interleukin 8 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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IL8 / Interleukin 8 Mouse anti-Human Monoclonal (3E4D8) Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$380
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IL8 / Interleukin 8 Rabbit anti-Chicken Polyclonal Antibody
Chicken
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
IL8 / Interleukin 8 Antibody - Western blot of recombinant IL8.
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IL8 / Interleukin 8 Mouse anti-Rabbit Monoclonal (aa23-101) Antibody
Rabbit
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
Viewing 1-25 of 416 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).