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IL6ST / CD130 / gp130
interleukin 6 signal transducer (gp130, oncostatin M receptor)
IL6ST / CD130 / gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
| Gene Name: | interleukin 6 signal transducer (gp130, oncostatin M receptor) |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL6ST, CD130, CD130 antigen, IL-6R subunit beta, IL-6 receptor subunit beta, Membrane glycoprotein gp130, Membrane glycoprotein 130, IL-6RB, CDW130, gp130, IL-6R-beta |
| Target Sequences: | NM_002184 NP_002175.2 P40189 |
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IL6ST / CD130 / gp130
(139)
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(71)
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IL6ST / CD130 / gp130 Mouse anti-Human Monoclonal (8D4D2) Antibody
Human, Monkey
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µg/$459
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal (aa748-797) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal (pTyr905) Antibody
Human
DB
Unconjugated
200 µl/$734
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC-P, WB
Unconjugated
50 µl/$460
Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
IL6ST / CD130 / gp130 Mouse anti-Human Monoclonal (8D4C5) Antibody
Human, Monkey
ELISA, Flo, ICC, WB
Unconjugated
100 µg/$459
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal (aa158-207) Antibody
Human
WB
Unconjugated
100 µl/$424
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal (aa158-207) (FITC) Antibody
Rabbit, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
Sandwich
96-Well Strip Plate
Human
0.25 - 16 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Sandwich
96-Well Microplate
Human
8.23 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal (p782) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$357
IL6ST / CD130 / gp130 Rabbit anti-Mouse Monoclonal (Preservative Free) (223) Antibody
Mouse
IHC-P
Unconjugated, Preservative Free
100 µl/$412
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal (pTyr905) Antibody
Human
DB
Unconjugated
400 µl/$393
HEK 293 Cells
6His, N-terminus
68 kDa
200 µl/$283
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal (aa871-899) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human, Monkey
ELISA, WB
Unconjugated
100 µl/$688
IL6ST / CD130 / gp130 Rabbit anti-Mouse Monoclonal (Preservative Free) (022) Antibody
Mouse
Flo
Unconjugated, Preservative Free
100 µl/$412
IL6ST / CD130 / gp130 Rabbit anti-Rat Monoclonal (Preservative Free) (108) Antibody
Rat
ELISA, Flo
Unconjugated, Preservative Free
100 µl/$412
IL6ST / CD130 / gp130 Rabbit anti-Mouse Monoclonal (Preservative Free) (001) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
IL6ST / CD130 / gp130 Mouse anti-Human Monoclonal (Biotin) (AN-G30) Antibody
Human
Flo
Biotin Conjugated
25 µg/$285; 100 µg/$375
IL6ST / CD130 / gp130 Rabbit anti-Mouse Monoclonal (PE) (022) Antibody
Mouse
Flo
PE Conjugated
25 Tests/$263; 100 Tests/$376
IL6ST / CD130 / gp130 Rabbit anti-Human Monoclonal (Preservative Free) (014) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
IL6ST / CD130 / gp130 Rabbit anti-Mouse Monoclonal (APC) (022) Antibody
Mouse
Flo
APC Conjugated
25 Tests/$263; 100 Tests/$376
IL6ST / CD130 / gp130 Rabbit anti-Human Polyclonal (720-800 aa) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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product results
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