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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL6R / IL6 Receptor Antibody (Extracellular Domain) LS‑C70920
Antibody
IL6 Receptor antibody LS-C70920 is an unconjugated rat monoclonal antibody to mouse IL6 Receptor (IL6R). Validated for ELISA and WB. Cited in 1 publication.
Catalog
Size
Price
LS-C70920-100
100 µg (0.5 mg/ml)
Unavailable

Popular IL6R / IL6 Receptor Products

Antibody
Species: Human
Applications: ICC, Flow Cytometry, ELISA
Antibody
Species: Human
Applications: Flow Cytometry, ELISA, Neutralization
Antibody
Species: Human
Applications: IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry, ELISA
Anti-IL6R antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6362 concentration 2.5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

IL6 Receptor antibody LS-C70920 is an unconjugated rat monoclonal antibody to mouse IL6 Receptor (IL6R). Validated for ELISA and WB. Cited in 1 publication.
About IL6R / IL6 Receptor
IL6R / IL6 Receptor is a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. P08887 NM_000565 NP_000556.1

IL6R Antibody, CD126 Antibody, gp80 Antibody, IL-6R subunit alpha Antibody, IL-6R-alpha Antibody, IL-6RA Antibody, IL6Q Antibody, IL-6 receptor subunit alpha Antibody, IL-6R 1 Antibody, IL-6R-1 Antibody, Interleukin 6 receptor Antibody, Membrane glycoprotein 80 Antibody, CD126 antigen Antibody, IL6RA Antibody, IL6RQ Antibody


Specifications

Target
Mouse IL6R / IL6 Receptor
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
Immunogen
NS0-derived rmIL-6Ralpha extracellular domain (aa 20-357) P22272
Epitope
Extracellular Domain
Specificity
Recognizes mouse IL-6Ralpha. In direct ELISAs and Western Blots, this antibody does not cross-react with rhIL-6R.
Usage
Western Blot: This antibody can be used at 1-2 ug/mL with the appropriate secondary reagents to detect mouse IL-6 R. Using a colorimetric detection system, the detection limit for rmIL-6 R is approximately 25 ng/lane under non-reducing and reducing conditions. Chemiluminescent detection will increase sensitivity by 5 to 50 fold. Direct ELISA: This antibody can be used at 0.5-1.0 ug/mL with the appropriate secondary reagents to detect mouse IL-6 R. The detection limit for rmIL-6 R is approximately 5 ng/well.
Presentation
Lyophilized from PBS, pH 7.4, 5% trehalose.
Reconstitution
200ul sterile PBS
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130. Wang X, Miller EB, Goswami M, Zhang P, Ronning KE, Karlen SJ, Zawadzki RJ, Pugh EN Jr, Burns ME. Journal of neuroinflammation. 2017 14:121. (WB; Mouse) [Full Text Article] [PubMed:28645275] [PMC:PMC5481880]

Customer Reviews (0)


Requested From: 
Date Requested: 6/19/2018

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