Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone MP5-32C11] (IgG2a) to Mouse IL6 / Interleukin 6
Western blot, Immunoprecipitation, Functional Assay
Mouse IL6 / Interleukin 6
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MP5-32C11]
Specificity and Use
Mouse IL6 / IL-6
For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralization of biological activity dilutions have to be made according to the amount of IL-6 to be inactivated.
Lyophilized from PBS
Sterile distilled water
Store lyophilized product at 4°C. Aliquot and store at -20°C after reconstitution. Avoid freeze-thaw cycles. Stable for one year.
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine.