Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone B-E8] (IgG1) to Human IL6 / Interleukin 6
IHC - Frozen, ELISA, Neutralization
Human IL6 / Interleukin 6
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [B-E8]
Ion exchange chromatography
IHC - Frozen
Specificity and Use
IL6 / Interleukin 6 antibody was raised against human recombinant IL-6.
Recognizes natural and recombinant human IL-6. Species cross-reactivity: Does not cross-react with mouse.
Suitable for use in Immunohistochemistry, ELISA and Neutralization Assays. Immunohistochemistry: Frozen. Neutralizing Assay: 20pg neutralizes activity of 1U of IL-6. Note: Removal of azide is required.
PBS, pH 7.2, 0.09% sodium azide
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine.