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IL5

interleukin 5 (colony-stimulating factor, eosinophil)

IL5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

Gene Name: interleukin 5 (colony-stimulating factor, eosinophil)
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL5, EDF, Interleukin-5, IL-5, T-cell replacing factor, TRF
Target Sequences: NM_000879 NP_000870.1 P05113

Publications (1)

1
The Chronic Stages of Bovine Fasciola hepatica Are Dominated by CD4 T-Cell Exhaustion. Sachdev D, Gough KC, Flynn RJ. Frontiers in immunology. 2017 August;8:1002. [Full Text Article] [PubMed:28871261] [PMC:PMC5566560]

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IL5 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IL5 Rabbit anti-Human Polyclonal (aa43-92) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
IL5 Antibody - Western Blot (non-reducing) of IL-5 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL5 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
IL5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
IL5 ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
IL5 Antibody - Immunohistochemical analysis of IL-5 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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IL5 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
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IL5 Rat anti-Human Monoclonal (Azide-free, Low Endotoxin) (TRFK5) Antibody
Mouse, Human
Depl, Flo, Neut
Unconjugated, Azide-free, Low Endotoxin
50 µg/$258; 500 µg/$408; 1 mg/$508
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IL5 Rat anti-Mouse Monoclonal (TRFK5) Antibody
Mouse, Human
ELISA, Flo, IF, WB
Unconjugated
0.5 mg/$387
IL5 ELISA Kit
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Sandwich
96-Well Strip Plate
Canine
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$911
IL5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
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IL5 Rat anti-Human Monoclonal (PerCP) (TRFK5) Antibody
Human
ELISA, Flo, IHC, WB
PerCP Conjugated
25 µg/$236; 100 µg/$259
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IL5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC-P, WB
Unconjugated
0.1 mg/$558
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IL5 Rat anti-Mouse Monoclonal Antibody
Mouse, Guinea pig, Human
ELISA, Flo, WB
Unconjugated
500 µg/$919
IL5 Antibody - 1:100 staining human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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IL5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL5 Antibody - Western blot of IL-5 antibody
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IL5 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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IL5 Rat anti-Human Monoclonal (SPM462) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$458
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IL5 Rabbit anti-Human Monoclonal (Preservative Free) (R013) Antibody
Human
Block, ELISA, Neut
Unconjugated, Preservative Free
200 µg/$398; 500 µg/$511
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IL5 Rabbit anti-Mouse Monoclonal (Preservative Free) (121) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
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IL5 Rat anti-Mouse Monoclonal Antibody
Mouse, Human
ELISA, Flo, IF, WB
Unconjugated
500 µg/$523
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IL5 Rat anti-Mouse Monoclonal (Azide-free) Antibody
Mouse, Human
ELISA, Flo, IF, Neut, WB
Unconjugated, Azide-free
500 µg/$563
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IL5 Rabbit anti-Human Monoclonal (Preservative Free) (001) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$286; 100 µl/$435
IL5 Antibody - Anti-IL5 rabbit monoclonal antibody at 1:500 dilution. Lane A: Hela Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 15 kDa. Observed band size: 20 kDa.
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IL5 Rabbit anti-Human Monoclonal (Preservative Free) (225) Antibody
Human
WB
Unconjugated, Preservative Free
100 µl/$412
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IL5 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
500 µg/$1,089
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IL5 Rat anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, WB
Unconjugated
500 µg/$523
IL5 Antibody - Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL5 Rabbit anti-Human Polyclonal (aa74-123) (FITC) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 189 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).