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IL4R / CD124
interleukin 4 receptor
IL4R / CD124 is the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
| Gene Name: | interleukin 4 receptor |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL4R, CD124, CD124 antigen, IL-4RA, IL4R nirs variant 1, IL4RA, Interleukin 4 receptor, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha |
| Target Sequences: | NM_000418 NP_000409.1 P24394 |
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IL4R / CD124 Mouse anti-Human Monoclonal (Extracellular Domain) (25463 (49/20)) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
0.1 mg/$414
IL4R / CD124 Rabbit anti-Rat Polyclonal (aa26-232) Antibody
Rat
WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331
IL4R / CD124 Rabbit anti-Rat Polyclonal (aa26-232) (Biotin) Antibody
Rat
WB
Biotin Conjugated
100 µl/$328; 200 µl/$378; 500 µl/$545; 1 ml/$645; 2 ml/$879; 5 ml/$1,464
IL4R / CD124 Mouse anti-Human Monoclonal (aa26-135) (1D3) Antibody
Human
ELISA
Unconjugated
100 µg/$423
IL4R / CD124 Mouse anti-Human Monoclonal (Extracellular Domain) Antibody
Human
ELISA, Flo, Func, IHC, IHC-P, WB
Unconjugated
100 µg/$658
IL4R / CD124 Rabbit anti-Human Polyclonal (aa463-512) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IL4R / CD124 Rabbit anti-Human Polyclonal (aa677-691) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
IL4R / CD124 Rabbit anti-Human Polyclonal (aa105-131) Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
293T Cells
Myc-DDK (Flag)
89.66 kDa
20 µg/$215
IL4R / CD124 Rabbit anti-Human Polyclonal (pTyr497) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IL4R / CD124 Rabbit anti-Human Monoclonal (aa1-232) (Preservative Free) (R401) Antibody
Human
Block, ELISA, Neut
Unconjugated, Preservative Free
200 µg/$398; 500 µg/$511
IL4R / CD124 Rabbit anti-Human Monoclonal (aa1-232) (Preservative Free) (R001) Antibody
Human
Block, ELISA, Neut
Unconjugated, Preservative Free
200 µg/$361; 500 µg/$436
IL4R / CD124 Rabbit anti-Rat Monoclonal (Preservative Free) (002) Antibody
Rat
ELISA, Flo
Unconjugated, Preservative Free
100 µl/$412
IL4R / CD124 Rabbit anti-Mouse Polyclonal (aa26-233) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
IL4R / CD124 Goat anti-Mouse Polyclonal (Extracellular Domain) (PE) Antibody
Mouse
Flo
PE Conjugated
100 Tests/$824
IL4R / CD124 Rabbit anti-Human Monoclonal (aa1-232) Antibody
Human
ELISA
Unconjugated
20 µl/$271; 100 µl/$412
IL4R / CD124 Rabbit anti-Human Monoclonal (APC) (209) Antibody
Human
Flo
APC Conjugated
25 Tests/$278; 100 Tests/$421
IL4R / CD124 Rabbit anti-Human Polyclonal (pTyr497) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IL4R / CD124 Rabbit anti-Rat Monoclonal (PE) (002) Antibody
Rat
Flo
PE Conjugated
25 Tests/$293; 100 Tests/$376
Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
IL4R / CD124 Goat anti-Mouse Polyclonal (Extracellular Domain) Antibody
Mouse
ELISA, Flo, WB
Unconjugated
100 µg/$930
IL4R / CD124 Rabbit anti-Human Polyclonal (440-520 aa) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IL4R / CD124 Rabbit anti-Human Polyclonal (pTyr497) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
IL4R / CD124 Rabbit anti-Human Polyclonal (Gly493) Antibody
Mouse, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
IL4R / CD124 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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product results
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