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Anti-IL4R / CD124 Antibody (Extracellular Domain, clone 49/20) LS-C11209


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $470
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular IL4R / CD124 Antibodies

Anti-IL4R / CD124 Antibody (Extracellular Domain, clone 49/20) LS-C11209
Mouse Monoclonal [clone 49/20] (IgG1) to Human IL4R / CD124
IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Anti-IL4R / CD124 Antibody (aa26-232) LS-C294912
Rabbit Polyclonal (IgG) to Rat IL4R / CD124
Western blot, ELISA
Western blot Image
Anti-IL4R / CD124 Antibody (aa26-232, Biotin) LS-C300802
Rabbit Polyclonal (IgG) to Rat IL4R / CD124
Western blot, ELISA
Biotin Conjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 49/20] (IgG1) to Human IL4R / CD124
IHC - Paraffin, Western blot, Flow Cytometry, ELISA


Human IL4R / CD124
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [49/20]
Protein A purified


  • IHC - Paraffin (1:40 - 1:125)
  • Western blot (1:250 - 1:1000)
  • Flow Cytometry (1:20 - 1:80)
  • ELISA (1:500 - 1:2000)

Specificity and Use

IL4R / CD124 antibody was raised against sf 21-derived, recombinant human interleukin 4 receptor, extracellular domain.
Extracellular Domain
Recognizes human Interleukin-4 receptor subunit alpha, also known as CD124. CD124 is a 825 amino acid ~90kD type I single pass transmembrane glycoprotein bearing a single domain. Interleukin-4 Receptor form a heterodimeric complex with the, referred to as the IL-4 type-1 complex. The alpha subunit can also form the type-II complex through association with the IL-13 receptor alpha 1 subunit. The IL-4R complex acts as a receptor for both interleukin-4 and interleukin-13. IL-4 R is expressed by B cells, T cells, monocytes and macrophages. Is reported to block human cell surface IL-4 receptor mediated bioactivities induced by IL-4 or IL-13. An ND50 was observed at approximately 5-20 ng/ml in the presence of 0.2 ng/ml of IL-4 using the factor dependant human erythroleukemic cell line, TF-1.
Western Blot: Will detect human IL-4 R under non-reducing conditions.


PBS, 0.09% sodium azide, 10% trehalose
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About IL4R / CD124

P24394 NM_000418 NP_000409.1

IL4R Antibody, CD124 Antibody, CD124 antigen Antibody, IL-4RA Antibody, IL4R nirs variant 1 Antibody, IL4RA Antibody, Interleukin 4 receptor Antibody, IL-4 receptor subunit alpha Antibody, IL-4R subunit alpha Antibody, IL-4R-alpha Antibody

IL4R / CD124 is the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.

Requested From: United States
Date Requested: 10/21/2016

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