Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone MP4-25D2] (IgG1,k) to Human IL4
Human, Monkey (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [MP4-25D2]
Specificity and Use
IL4 antibody was raised against cHO-expressed recombinant human IL-4
In sandwich ELISA, this antibody should be paired with a suitable purified antibody as the capture antibody, with purified recombinant human IL-4 as the standard. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine.