Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IL36B Antibody, FIL1 Antibody, FIL1 eta Antibody, FILI-(ETA) Antibody, IL-1 eta Antibody, IL-1F8 Antibody, Interleukin 1, eta Antibody, Interleukin-1 eta Antibody, IL1F8 Antibody, Interleukin 36, beta Antibody, Interleukin-1 family member 8 Antibody, Interleukin-1 Superfamily e Antibody, Family of interleukin 1-eta Antibody, FIL1H Antibody, Interleukin-1 homolog 2 Antibody, FIL1-(ETA) Antibody, IL-1F8 (FIL1-eta) Antibody, IL-1H2 Antibody, IL1-ETA Antibody, IL1H2 Antibody, Interleukin-36 beta Antibody
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP.
Western blot of IL1F8 (arrow) using rabbit polyclonal IL1F8 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the IL1F8 gene (Lane 2).
IL1F8 Antibody flow cytometry of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.