Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone MRC OX-39] (IgG1) to Rat IL2RA / CD25
IHC - Paraffin, IHC - Frozen, Flow Cytometry
Rat IL2RA / CD25
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MRC OX-39]
Protein G purified
IHC - Paraffin
IHC - Frozen
Flow Cytometry (0.1 µg/10E6 cells)
Specificity and Use
IL2RA / CD25 antibody was raised against t blasts from a mixed lymphocyte reaction between purified CD4 positive T cells and irradiated spleens.
Anti-rat CD25 (IL-2R) monoclonal antibody recognizes the smaller (alpha subunit) 55kD chain of the IL-2 receptor found on activated rat T cells, thymic dendritic cells but not resting lymphocytes. The antibody binds to the rat interleukin-2 receptor desig.
PBS, no preservative.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.