IL28B

interferon, lambda 3

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

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Products

Antibodies (35)

ELISA Kits (10)

Proteins (9)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (35)

Recombinant (7)

Sandwich (7)

Sandwich CLIA (2)

Target

IL28B (54)

Reactivity

Human (42)

Mouse (12)

Rat (6)

Chimpanzee (3)

Gibbon (3)

Application

IHC (7)

IHC-P (2)

WB (26)

ELISA (16)

ICC (8)

IF (3)

IP (8)

Peptide-ELISA (1)

Host

rabbit (26)

mouse (9)

Isotype

IgG (15)

IgG2b (1)

Clonality

monoclonal mc (9)

polyclonal pc (26)

Clone

18 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Strip Plate (9)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Preservative Free (2)

Unconjugated (20)

more less

Epitope

aa34-63 (7)

C-Terminus (4)

aa22-196 (1)

Publications

No (54)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (4)

Plasma (9)

Serum (9)

Tissue Homogenates (3)

Tag

6His, C-terminus (3)

His (1)

Myc-DDK (Flag) (2)

Species

Human (8)

Source

293T Cells (1)

CHO Cells (1)

HEK 293 Cells (1)

Human Cells (2)

Insect Cells (1)

Mammalian Cells (3)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (2)

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Human IL28B (CLIA) ELISA Kit - LS-F26382

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$968

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IL28B Antibody LS-C482478

Antibody:

IL28B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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IL28B Antibody LS-C767412

Antibody:

IL28B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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IL28B Antibody LS-C807519

Antibody:

IL28B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Human IL28B (Sandwich ELISA) ELISA Kit - LS-F11775

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human IL28B (Sandwich ELISA) ELISA Kit - LS-F4455

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$671

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Human IL28B (Sandwich ELISA) ELISA Kit - LS-F646

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$618

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IL28B Antibody LS-C334190

Antibody:

IL28B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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IL28B Antibody LS-C201131

Antibody:

IL28B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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IL28B Antibody LS-C664010

Antibody:

IL28B Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

500 µl/$507; 1 ml/$581

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IL28B Antibody (HRP) LS-C710899

Antibody:

IL28B Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$345; 200 µl/$403; 1 ml/$742

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IL28B Antibody (Biotin) LS-C686666

Antibody:

IL28B Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Biotin Conjugated

Price:

200 µl/$374; 500 µl/$537; 1 ml/$628

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IL28B Antibody (FITC) LS-C693393

Antibody:

IL28B Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

FITC Conjugated

Price:

200 µl/$418; 500 µl/$638; 1 ml/$798

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IL28B Antibody (Cy3) LS-C701876

Antibody:

IL28B Mouse anti-Human Monoclonal (Cy3) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Cy3 Conjugated

Price:

200 µl/$507; 500 µl/$887; 1 ml/$1,051

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IL28B Antibody (APC) LS-C740254

Antibody:

IL28B Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

APC Conjugated

Price:

200 µl/$507; 500 µl/$887; 1 ml/$1,051

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IL28B Antibody (APC, Cy7) LS-C733941

Antibody:

IL28B Mouse anti-Human Monoclonal (APC, Cy7) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

APC, Cy7 Conjugated

Price:

1 ml/$1,481

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IL28B Antibody (PE) LS-C724961

Antibody:

IL28B Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

PE Conjugated

Price:

200 µl/$507; 500 µl/$887; 1 ml/$1,051

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3
• APC
• APC, Cy7
• More...
  • PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3
  • APC
  • APC, Cy7
  • PE

Select

IL28B Antibody LS-C747977

Antibody:

IL28B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

IL28B Antibody LS-C835018

Antibody:

IL28B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

IL28B Antibody (aa22-196) LS-C378049

Antibody:

IL28B Rabbit anti-Human Polyclonal (aa22-196) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

IL28B Antibody LS-C754498

Antibody:

IL28B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$406

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IL28B Antibody (aa34-63) LS-C322222

Antibody:

IL28B Rabbit anti-Human Polyclonal (aa34-63) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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IL28B Antibody (aa34-63, Biotin) LS-C246783

Antibody:

IL28B Rabbit anti-Human Polyclonal (aa34-63) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

IL28B Antibody (aa34-63, APC) LS-C246782

Antibody:

IL28B Rabbit anti-Human Polyclonal (aa34-63) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• APC

• Unconjugated
• Biotin
• APC

Select

IL28B Antibody LS-C781116

Antibody:

IL28B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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