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Anti-IL23R Antibody (aa59-87) LS-C187852


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $370
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular IL23R Antibodies

Anti-IL23R Antibody (aa24-354) LS-C37068
Mouse Monoclonal (IgG2b) to Human IL23R
Western blot, ELISA
Western blot Image
Anti-IL23R Antibody (clone 218213, PE) LS-C37069
Mouse Monoclonal [clone 218213] (IgG2b) to Human IL23R
Flow Cytometry
PE Conjugated
Flow Cytometry Image
Anti-IL23R Antibody (aa59-87) LS-C187852
Goat Polyclonal (IgG) to Human IL23R
Human, Mouse
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human IL23R
Human, Mouse
IHC - Paraffin, Western blot


Human IL23R
Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Affinity purified


  • IHC - Paraffin (1:125)
  • Western blot (1:500)

Specificity and Use

IL23R antibody was raised against synthetic peptide CQPRKLHFYKNGIKERFQITRINKTTARL corresponding to amino acids 59-87 within the N-terminal region of human IL-23 receptor. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan (100%); Marmoset, Dog (97%); Gibbon, Monkey, Panda (93%); Ferret, Bovine, Cat, Horse, Pig (90%).
Recognizes the human interleukin-23 receptor (IL-23R). The interleukin-23 receptor is 629 amino acid ~72kD single pass type I transmembrane glycoprotein belonging to the type I cytokine receptor family and possessing two domains. Multiple potential isoforms formed by alternative splicing are described. Recognizes an epitope within the N-terminal (NT) region of Interleukin-23 receptor (IL-23R), present in isoforms 1, 3 and 4, the antibody is not expected to recognize other truncated forms of the receptor lacking the immunogen sequence. IL-23R is a mediator of T-cell, NK cell, and possibly macrophage/myeloid cell, stimulation acting as the receptor for IL-23, by association with the beta component of IL-12R and is thought to signal through activation of the JAK-STAT signalling pathway. Genetic variation in IL23R is associated with inflammatory bowel disease type 17 and susceptibility to the ulcerative and inflammatory psoriasis. Is reported as suitable for use in immunocytochemistry on acetone fixed cells and has been used successfully for the immunohistochemical localization of IL-23R in formalin fixed, paraffin embedded human tissues.
Use in IHC requires heat treatment prior to staining.


PBS, 0.1% sodium azide, 0.1% BSA
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About IL23R

Q5VWK5 NM_144701 NP_653302.2

IL23R Antibody, IL-23 receptor Antibody, Interleukin 23 receptor Antibody, IBD17 Antibody, IL-23R Antibody, Interleukin-23 receptor Antibody

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.


Immunohistochemistry of paraffin-embeddedi mouse spleen stained with Goat anti-human IL-23 Receptor


Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-human IL-23 Receptor

Requested From: United States
Date Requested: 10/25/2016

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