LSBio
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA and Assay Kits
  • All Kits
  • Assay Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

Anti-IL23A / IL-23 p19 Antibody (clone HLT2736) IHC-plus™ LS-B3708

Note: This antibody replaces LS-C40934
Catalog Size Price
LS-B3708-50 50 µg (0.5 mg/ml) Unavailable

Most Popular IL23A / IL-23 p19 Antibodies

Anti-IL23A / IL-23 p19 Antibody (N-Terminus) IHC-plus™ LS-B573
Rabbit Polyclonal to Human IL23A / IL-23 p19
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-IL23A / IL-23 p19 Antibody (C-Terminus) IHC-plus™ LS-B1366
Rabbit Polyclonal to Human IL23A / IL-23 p19
Human
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-IL23A / IL-23 p19 Antibody (clone 473P19) LS-C107124
Mouse Monoclonal [clone 473P19] (IgG1,k) to Human IL23A / IL-23 p19
Human
Western blot, ELISA, Sandwich ELISA
Unconjugated
Anti-IL23A / IL-23 p19 Antibody (clone HLT2736) IHC-plus™ LS-B3708
Mouse Monoclonal [clone HLT2736] (IgG1) to Human IL23A / IL-23 p19
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-IL23A / IL-23 p19 Antibody (Biotin) LS-C527283
Rabbit Polyclonal (IgG) to Human IL23A / IL-23 p19
Human, Mouse
IHC, Western blot
Biotin Conjugated

100% Guaranteed Publications (3)
Mouse Monoclonal [clone HLT2736] (IgG1) to Human IL23A / IL-23 p19
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human IL23A / IL-23 p19
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [HLT2736]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot

Specificity and Use

Recombinant human IL23A / IL-23.
Human recombinant p40 and p19 with elastin linker
Immunohistochemistry: LS-B3708 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3708 was determined to be 10 ug/ml.

Packaging

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide. Sourced in TCS.
+4°C. Store undiluted.
For research use only.

Publications (3)

1
The involvement of IL-23 and the Th17 pathway in periodontitis. Ohyama H, Kato-Kogoe N, Kuhara A, Nishimura F, Nakasho K, Yamanegi K, Yamada N, Hata M, Yamane J, Terada N. Journal of dental research. 2009 88:633-8. [PubMed:19605880]
2
Systemic and local interleukin-17 and linked cytokines associated with Sjgren's syndrome immunopathogenesis. Katsifis GE, Rekka S, Moutsopoulos NM, Pillemer S, Wahl SM. The American journal of pathology. 2009 175:1167-77. [PubMed:19700754] [PMC:PMC2731135]
3
Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin. Muehlbauer SM, Lima H, Goldman DL, Jacobson LS, Rivera J, Goldberg MF, Palladino MA, Casadevall A, Brojatsch J. The American journal of pathology. 2010 177:735-43. [PubMed:20595632] [PMC:PMC2913046]

About IL23A / IL-23 p19

Q9NPF7 NM_016584 NP_057668.1

IL23A Antibody, IL-23 subunit alpha Antibody, IL-23A Antibody, Interleukin 23 p19 subunit Antibody, Interleukin-23 subunit alpha Antibody, IL23P19 Antibody, Interleukin-23 subunit p19 Antibody, p19 Antibody, SGRF Antibody, IL-23 Antibody, IL-23 p19 Antibody, IL-23-A Antibody, IL-23p19 Antibody

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines.

Immunohistochemistry

Immunohistochemistry
Anti-IL-23 p19 antibody IHC of human lung, vasculature. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3708 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-IL-23 p19 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3708 concentration 10 ug/ml.

Western blot

Western blot
Linker-free, recombinant human IL-23 was resolved by electrophoresis, transferred to nitrocellulose and probed with the anti-IL23 p19 specific antibody HLT2736 antibody. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a ch.

Requested From: 
Date Requested: 10/19/2017

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2017 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number