Human IL22RA1 / IL22R

Goat

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Affinity purified

Unmodified

Synthetic peptide DSGPEGTPDTVYSIEYKTYGERDWVAKKG corresponding to amino acids 42-70 within the N-Terminus of human IL-22 receptor. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey (100%); Gibbon, Marmoset (93%).

aa42-70

Recognizes an epitope within the N-terminal (NT) region of human interleukin-22 receptor (IL-22R), also known as IL-22R alpha-1 (IL22RA1), a member of the type II cytokine receptor family, which signals via the JAK-STAT signalling pathway. IL-22R acts as the functional receptor for IL-22, through association with the beta chain of the IL-10R, and as a receptor for IL-20 and IL-24 through association with the beta chain of IL-20R. Binding of IL-22 to functional IL-22R can be blocked by a soluble form of the receptor known as IL22 binding protein (IL22BP).

• IHC
• IHC - Paraffin (1:150)
• Immunofluorescence (1:100)
• ELISA (1:50000)

PBS, 0.1% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q8N6P7 NCBI: NM_021258 NP_067081.2