Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone JES6-1A12] (IgG2a,k) to Mouse IL2
Western blot, Sandwich ELISA
Mouse (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [JES6-1A12]
Specificity and Use
IL2 antibody was raised against e. coli-expressed recombinant mouse IL-2
In sandwich ELISA pair with biotinylated JES-5H4 antibody as the detection antibody, with purified recombinant mouse IL-2 as the standard. Useful in western blot in conjunction with AP-labeled Goat Anti-Rat-Ig, under reducing conditions.
Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene.