Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Western blot, Functional Assay, Immunodiffusion, Neutralization
Mouse (tested or 100% immunogen sequence identity)
Western blot (1:10)
Specificity and Use
Binds to soluble mouse interleukin-1 receptor type I.
Can be used for Western Blot. Furthermore the antibody is useful for inhibition in biological assays, in vitro as well as in vivo. Western Blot: 1:10. For Neutralization of biological activity dilutions have to be made according to the amounts IL-1 RI to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.
PBS, 0.02% sodium azide, 0.1% BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
IL1R1 Antibody, Antigen CD121a Antibody, D2S1473 Antibody, IL-1R-1 Antibody, IL-1R-alpha Antibody, IL-1RT-1 Antibody, IL-1RT1 Antibody, IL1R Antibody, IL1RA Antibody, IL1RT1 Antibody, Interleukin receptor 1 Antibody, Interleukin-1 receptor alpha Antibody, Interleukin-1 receptor type 1 Antibody, CD121A Antibody, CD121a antigen Antibody, Interleukin 1 receptor, type I Antibody, Interleukin-1 receptor type I Antibody, Interleukin-1 type i receptor Antibody, p80 Antibody
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits.