Mouse IL1R1

Hamster

Mouse (tested or 100% immunogen sequence identity)

IgG Monoclonal

JAMA-147

Unconjugated

Protein G purified

Unmodified

Extracellular domain of murine IL-1R

Extracellular Domain

Recognizes murine CD121a, which is the 80kD type I interleukin-1 receptor. CD121a is weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members; IL-1 alpha; IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a. Clone JAMA-147 has been reported to block IL-1 dependent cellular responses. XXX recommend the use of MCA2352EL for this purpose.

• Immunoprecipitation
• Flow Cytometry (1:25 - 1:100)

Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P14778 NCBI: NM_000877 NP_000868.1