Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 4K5F6] (IgG2b,k) to Human IL17A
IHC, IHC - Paraffin, Western blot
Mouse Monoclonal (IgG1) to Human IL17A
Human (tested or 100% immunogen sequence identity)
Specificity and Use
IL17A antibody was raised against human IL-17.
Recognizes human IL-17.
Suitable for use in Flow Cytometry. Flow Cytometry: Neat. 10 ul labels 5x10^5 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
IL17A is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.