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Anti-IL17A Antibody LS-C37029

Ordering

Wt. Vol. Conc. Price
100 µg - 0.2 mg/ml $695
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular IL17A Antibodies

Anti-IL17A Antibody IHC-plus™ LS-B7397
Rabbit Polyclonal (IgG) to Human IL17A
Human
IHC - Paraffin, Western blot, ELISA, Neutralization
Unconjugated
Immunohistochemistry Image
Anti-IL17A Antibody (Biotin) LS-C154151
Rabbit Polyclonal (IgG) to Rat IL17A
Rat, Mouse
IHC, Western blot, ELISA
Biotin Conjugated
Western blot Image
Anti-IL17A Antibody (aa1-75, clone 4K5F6) IHC-plus™ LS-B8323
Mouse Monoclonal [clone 4K5F6] (IgG2b,k) to Human IL17A
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human IL17A
Human
ICC, Western blot, Flow Cytometry, ELISA, Neutralization
Unconjugated

Details

Human IL17A
Goat
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • ICC (2 - 15 µg/ml)
  • Western blot (0.1 - 0.2 µg/ml)
  • Flow Cytometry
  • ELISA (0.5 - 1 µg/ml)
  • Neutralization

Specificity and Use

IL17A antibody was raised against purified, E. coli-derived, recombinant human interleukin 17.
Recognizes human IL-17.
Suitable for use in Neutralization, Western Blot, Immunocytochemistry, Flow Cytometry, Direct ELISA. Neutralization: The ND50 is ~0.1-0.3 ug/ml in the presence of 25 ng/ml of rhIL-17, using the NHDF cell line. Immunocytochemistry: 2-15 ug/ml. Direct ELISA: 0.5-1 ug/ml with the appropriate secondary reagents to detect human IL-17. The detection limit for rhIL-17 is approximately 0.2 ng/well. In this format, this antibody shows approximately 10% cross-reactivity with rmIL-17 and rhIL-17F and less than 1% cross-reactivity with rhIL-17B, rhIL-17C, rhIL-17D and rhIL-17E. Western Blot: 0.1-0.2 ug/ml with the appropriate secondary reagents to detect human IL-17. The detection limit for rhIL-17 is approximately 5 ng/lane under both non-reducing and reducing conditions. Flow Cytometry: Tested in PBMCs. For intracellular staining to detect IL-17, cells must be first fixed and permeabilized using 4% paraformaldehyde and 0.1% saponin in PBS. Dilute this antibody to 50 ug/ml and add 10 ul of the diluted solution to 1-5 x 10^5 cells in a total reaction volume not exceeding 200ul. The binding of unlabeled polyclonal antibodies can be visualized by a secondary developing reagent such as anti-goat lgG conjugated to a fluorochrome.

Packaging

Lyophilized from PBS, pH 7.4, 5% trehalose
0.5 ml sterile PBS
For long term, store at -20°C. Avoid repeat freeze-thaw cycles.
For research use only.

About IL17A

Q16552 NM_002190 NP_002181.1

IL17A Antibody, CTLA-8 Antibody, CTLA8 Antibody, Interleukin-17A Antibody, Interleukin 17A Antibody, IL-17 Antibody, IL-17A Antibody, IL17 Antibody

IL17A is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Requested From: United States
Date Requested: 12/5/2016

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