Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [G11/II]
IHC - Paraffin (5 µg/ml)
Specificity and Use
IL16 antibody was raised against recombinant human IL-16
G11/II detects LCF, a homotetrameric glycoprotein of 56kDa molecular weight that is composed of four noncovalently linked peptides of 14 kDa. Specificity: Human: LCF (IL-16). Other species: not tested.
PBS pH 7.2, 0.1% sodium azide. Sourced in TCS.
Aliquot and store at -20°C. Minimize freezing and thawing.
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.Isoform 3 is involved in cell cycle progression in T-cells.