Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, Western blot, ELISA, Neutralization
Mouse Monoclonal (IgG1) to Human IL13
Human (tested or 100% immunogen sequence identity)
Specificity and Use
Recognizes human IL-13. Blocks IL-13 induced proliferation.
Suitable for use in Functional Studies. Functional Studies: Blocks IL-13 induced proliferation. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
50 mM Tris, 100 mM sodium chloride, 0.02% sodium azide, pH 7.4, 1% BSA.
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines.