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IL13 antibody LS-C58338 is an FITC-conjugated mouse monoclonal antibody to human IL13. Validated for Flow.
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Technical Help
Review This ProductPopular IL13 Products
Species:
Rat
Applications:
IHC, IHC - Paraffin, Flow Cytometry, ELISA
Species:
Human
Applications:
Immunofluorescence, Western blot, Flow Cytometry, ELISA, Sandwich ELISA
Species:
Human
Applications:
IHC, IHC - Frozen, Western blot, ELISA, Neutralization
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Product Description
IL13 antibody LS-C58338 is an FITC-conjugated mouse monoclonal antibody to human IL13. Validated for Flow.
About IL13
IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines.
P35225
NM_002188
NP_002179.2
IL13 Antibody, ALRH Antibody, BHR1 Antibody, Interleukin-13 Antibody, NC30 Antibody, p600 Antibody, IL-13 Antibody, Interleukin 13 Antibody
Specifications
Target
Human IL13
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
[B-P6]
Conjugations
Fluorescein
Purification
Ion exchange chromatography
Modifications
Unmodified
Applications
- Flow Cytometry
Immunogen
IL13 antibody was raised against recombinant human IL-13.
Specificity
Recognizes human interleukin-13 (IL-13), a 12.5kD immunoregulatory cytokine produced primarily by activated T helper type 2 (Th2) cells, and also by mast cells and NK cells. IL-13 induces the stimulation of B cell proliferation and antibody production, and studies suggest that IL-13 plays an important role in the induction of the pathophysiological features of allergic asthma, independently of Immunoglobulin E (IgE) and eosinophils.
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
Tris-sodium chloride, pH 7.4, 0.02% sodium azide, 1% BSA.
Storage
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
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