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IL13

interleukin 13

IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Gene Name: interleukin 13
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL13, ALRH, BHR1, Interleukin-13, NC30, p600, IL-13, Interleukin 13
Target Sequences: NM_002188 NP_002179.2 P35225

Publications (1)

1
A new heterotopic transplant animal model of intestinal fibrosis. Martin Hausmann, Thomas Rechsteiner, Michaela Caj, Christian Benden, Michael Fried, Annette Boehler, Gerhard Rogler. The Breast : official journal of the European Society of Mastology. 2013 Oct;;19:2302-14. [Full Text Article] [PubMed:24013360] Related Antibodies: LS-B3767.

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Antibodies (116)
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IL13 Antibody - Anti-IL-13 antibody IHC of rat spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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IL13 Mouse anti-Rat Monoclonal (5J56) Antibody
Rat
ELISA, Flo, IHC-P
Unconjugated
125 µg/$595
IL13 Antibody - Anti-IL-13 antibody IHC of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IL13 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
IL13 Antibody - Direct ELISA of IL-13 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL13 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
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IL13 Rat anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, SwELISA, WB
Unconjugated
250 µg/$459; 500 µg/$611
IL13 Antibody - IL13 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lung tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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IL13 Rabbit anti-Human Polyclonal (aa118-146) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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IL13 Rat anti-Human Monoclonal (JES10-5A2) Antibody
Human
ELISA, IHC, IHC-Fr, Neut, WB
Unconjugated
100 µg/$434; 500 µg/$866
IL13 Antibody - Immunohistochemistry of paraffin-embedded mouse brain tissue.
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IL13 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IL13 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
8.23 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$470
IL13 ELISA Kit
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Sandwich
96-Well Microplate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
IL13 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.164 - 40 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
IL13 ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
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IL13 Mouse anti-Human Monoclonal (Preservative Free) (4C10A7B3) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
IL13 Antibody - BALB/c splenocytes were cultured for 3 days with plate-bound anti-mouse CD3e (clone 145-2C11, ), soluble anti-mouse CD28 (clone 37.51), recombinant mouse IL-2, and recombinant mouse IL-4. Cells were then harvested and restimulated with PMA/Ionomycin in the presence of monensin for 5 hours. Following restimulation, cells were harvested, surface stained with FITC anti-mouse CD4 (clone RM4-5, LS-C106049), fixed and permeabilized, then stained with 0.125 ug PE antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL13 Rat anti-Mouse Monoclonal (PE) (13A) Antibody
Mouse
Flo
PE Conjugated
25 Tests/$279
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
14.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
IL13 Protein - Recombinant Interleukin 13 (IL13) by SDS-PAGE
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E. coli
His, N-Terminal
15.8kDa
10 µg/$286; 50 µg/$472; 200 µg/$942; 100 µg/$752; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
IL13 Antibody - Immunohistochemistry of paraffin-embedded human lung tissue at dilution of 1:100
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IL13 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
IL13 Antibody
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IL13 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
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IL13 Mouse anti-Human Monoclonal (3H7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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IL13 Rat anti-Human Monoclonal (JES10-35G12) Antibody
Human
ELISA
Unconjugated
0.5 mg/$534
IL13 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
IL13 Protein - Recombinant mouse IL-13 induces the proliferation of TF-1 cell in a dose-dependent manner. The ED50 for this effect is 0.3 - 1.5 ng/mL.
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E. coli
None
Biologically active
Less than 0.01 ng/µg (Less than 0.1 EU/µg) (determined by LAL method).
The 106 amino acid recombinant protein has a predicted molecular mass of 11,677 Da. The DTT-reduced protein migrates at approximately 9kDa and the non-reduced protein migrates at approximately 8kDa by SDS-PAGE. The N-terminal amino acid is Serine.
10 µg/$344; 25 µg/$478; 100 µg/$1,214; 500 µg/$2,539
IL13 Antibody - Western blot analysis of extracts of NCI-H460 cells, using IL13 antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
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IL13 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389; 200 µl/$503
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IL13 Mouse anti-Human Monoclonal (2B5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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IL13 Rat anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$568
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IL13 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
100 µl/$860
Viewing 1-25 of 221 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).