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IL12B / IL12 p40

interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)

IL12B / IL12 p40 is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.

Gene Name: interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
Family/Subfamily: Interleukin
Synonyms: IL12B, CLMF p40, IL-12 p40, IL-12 subunit p40, Interleukin-12 beta chain, Interleukin-12 subunit beta, IL12, subunit p40, Interleukinl-12, Interleukin 12, p40, NKSF, CLMF, CLMF2, IL-12B, NKSF2
Target Sequences: NM_002187 NP_002178.2 P29460

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Antibodies (124)
ELISA Kits (44)
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IL12B / IL12 p40 (191)
Human (53)
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IL12B / IL12 p40 Antibody - IL12B antibody immunohistochemistry of formalin-fixed and paraffin-embedded human tonsil tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
IL12B / IL12 p40 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using IL12B Antibody at dilution of 1:100
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IL12B / IL12 p40 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
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IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa23-328) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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IL12B / IL12 p40 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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IL12B / IL12 p40 Mouse anti-Human Monoclonal (I-1A4) Antibody
Human
ELISA, IHC-Fr
Unconjugated
0.5 mg/$534
IL12B / IL12 p40 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
IL12B / IL12 p40 Antibody - 1:100 staining human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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IL12B / IL12 p40 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL12B / IL12 p40 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$889
IL12B / IL12 p40 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
IL12B / IL12 p40 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
12.29 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
IL12B / IL12 p40 Antibody - IL12B / IL12p40 Antibody (4µg/ml) staining of paraffin embedded Human Colon. Steamed antigen retrieval with citrate buffer pH 9, HRP-staining.This data is from a previous batch, not on sale.
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IL12B / IL12 p40 Goat anti-Human Polyclonal (aa278-292) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µg/$503
IL12B / IL12 p40 Antibody - IL12B monoclonal antibody (M01), clone 2H6. Western Blot analysis of IL12B expression in HepG2.
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IL12B / IL12 p40 Mouse anti-Human Monoclonal (2H6) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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IL12B / IL12 p40 Rabbit anti-Mouse Polyclonal (aa196-222) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
200 µl/$952
IL12B / IL12 p40 Antibody - IL12B / IL12 p40 antibody (1µg/ml) staining of Rat Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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IL12B / IL12 p40 Goat anti-Mouse Polyclonal (aa211-222) Antibody
Mouse, Rat
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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IL12B / IL12 p40 Rabbit anti-Sheep Polyclonal Antibody
Sheep
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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IL12B / IL12 p40 Mouse anti-Human Monoclonal (Preservative Free) (6E3E1A8) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
Select
IL12B / IL12 p40 Mouse anti-Human Monoclonal (Preservative Free) (05) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$286; 100 µl/$435
IL12B / IL12 p40 Antibody - Western blot of recombinant IL12B / IL12 p40.
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IL12B / IL12 p40 Rabbit anti-Mouse Polyclonal (aa35-302) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
Select
IL12B / IL12 p40 Rabbit anti-Sheep Polyclonal (Biotin) Antibody
Sheep
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
IL12B / IL12 p40 Antibody - Western blot of IL12B / IL12 p40 antibody.
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IL12B / IL12 p40 Rabbit anti-Dog Polyclonal (aa23-329) Antibody
Dog
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
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IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
Select
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
Select
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Select
IL12B / IL12 p40 Rabbit anti-Rat Monoclonal (Preservative Free) (010) Antibody
Rat
ELISA
Unconjugated, Preservative Free
100 µl/$412
Select
IL12B / IL12 p40 Rabbit anti-Rat Monoclonal (Preservative Free) (106) Antibody
Rat
ELISA
Unconjugated, Preservative Free
100 µl/$412
Viewing 1-25 of 191 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).