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Anti-IL10RA Antibody (phospho-Ser323) LS-C205317

Catalog Size Price
LS-C205317-50 50 µl (1 mg/ml) Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human IL10RA
Human
Western blot
Unconjugated

Details

Human IL10RA
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (1:500 - 1:1000)

Specificity and Use

IL10RA antibody was raised against peptide sequence around phosphorylation site of Serine 319/Serine 323 (D-S (p) -G-F-G-S (p) -T) of human IL-10R subunit alpha.
pSer323
The antibody detects endogenous levels of IL-10R subunit alpha protein only when phosphorylated at serine 319 and serine 323.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only.

About IL10RA

Q13651 NM_001558 NP_001549.2

IL10RA Antibody, CD210 Antibody, CD210a Antibody, CD210 antigen Antibody, IBD28 Antibody, IL-10R subunit 1 Antibody, Il-10r Antibody, IL-10R subunit alpha Antibody, Interleukin 10 receptor, alpha Antibody, IL10R Antibody, Interleukin-10 receptor Antibody, HIL-10R Antibody, CDW210A Antibody, IL-10 receptor subunit alpha Antibody, IL-10R1 Antibody, IL-10RA Antibody, Interleukin-10 receptors Antibody

IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.

Requested From: 
Date Requested: 8/18/2017

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