Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Human IL-1B / IL-1 Beta
ICC, Functional Assay, Neutralization
Human IL-1B / IL-1 Beta
Human (tested or 100% immunogen sequence identity)
Specificity and Use
Recognizes human IL-1.
Suitable for use Immunocytochemistry, Neutralization and functional studies. Functional Application: 100 ng neutralizes 1 unit of IL-1 beta. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
IL-1 Beta is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.