Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IKZF1 / IKAROS is a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry - Paraffin
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot detection of Ikaros(C-terminus) in Ramos and Jurkat cell lysates using Ikaros(C-terminus) mouse monoclonal antibody (1:1000 dilution). Predicted band size: 58KDa. Observed band size: 58KDa.
Immunoprecipitation analysis of HeLa cell lysate using Ikaros (C-terminus) mouse monoclonal antibody.