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IK3-1 / CABLES1

Cdk5 and Abl enzyme substrate 1

Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.

Gene Name: Cdk5 and Abl enzyme substrate 1
Synonyms: CABLES1, CABL1, IK3-1, HsT2563, CABLES, Interactor with CDK3 1
Target Sequences: AA587396 Q8TDN4 Q8TDN4

☰ Filters
Antibodies (19)
Proteins (4)
Over-Expression Lysate (2)
Primary (19)
Recombinant (2)
IK3-1 / CABLES1 (23)
Human (19)
Mouse (12)
Rat (4)
Bovine (6)
Chicken (3)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Guinea pig (3)
Horse (3)
Monkey (6)
Orangutan (6)
Pig (3)
Rabbit (3)
Xenopus (3)
Zebrafish (3)
IHC (3)
IHC-P (1)
WB (19)
ELISA (3)
ICC (1)
IF (5)
Peptide-ELISA (3)
rabbit (17)
mouse (2)
IgG (8)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (18)
OTI2A3 (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (13)
aa214-263 (4)
aa516-565 (4)
530-610 aa, C-terminal (1)
C-Terminus (1)
Lys588 (1)
aa539-588 (1)
aa561-610 (1)
No (23)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
IK3-1 / CABLES1 Antibody - Immunohistochemical analysis of CABLES1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
IK3-1 / CABLES1 Antibody - IK3-1 / CABLES1 antibody Western Blot of RPMI-8226.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa214-263) Antibody
Human
WB
Unconjugated
100 µl/$424
IK3-1 / CABLES1 Antibody - IK3-1 / CABLES1 antibody Western Blot of RPMI-8226.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa214-263) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Orangutan, Gibbon, Chimpanzee
WB
HRP Conjugated
100 µl/$469
IK3-1 / CABLES1 Antibody - IK3-1 / CABLES1 antibody Western Blot of RPMI-8226.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa214-263) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Orangutan, Gibbon, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
IK3-1 / CABLES1 Antibody - IK3-1 / CABLES1 antibody Western Blot of RPMI-8226.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa214-263) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Orangutan, Gibbon, Chimpanzee
WB
FITC Conjugated
100 µl/$469
IK3-1 / CABLES1 Antibody - Western blot of Cables1 antibody
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (530-610 aa, C-terminal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IK3-1 / CABLES1 Antibody - Western blot of Cables1 (K588) pAb in extracts from LOVO cells.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (Lys588) Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
IK3-1 / CABLES1 Antibody - Staining LOVO cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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IK3-1 / CABLES1 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
IK3-1 / CABLES1 Antibody - Western blot analysis of Mouse brain and human fetal muscle tissue, mouse heart tissue, using CABLES1 Polyclonal Antibody at dilution of 1:650.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IK3-1 / CABLES1 Antibody - Western blot analysis of extracts from LOVO cells, using Ik3-1 antibody.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
IK3-1 / CABLES1 Antibody - Western blot analysis of lysates from LOVO cells, using Ik3-1 Antibody. The lane on the right is blocked with the synthesized peptide.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa561-610) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IK3-1 / CABLES1 Antibody - Western blot analysis of the lysates from HeLa cells using Ik3-1 antibody.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa539-588) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IK3-1 / CABLES1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY CABLES1. (Right lane) cDNA for 48 hrs and lysed
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IK3-1 / CABLES1 Mouse anti-Human Monoclonal (OTI2A3) Antibody
Human
WB
Unconjugated
100 µl/$434
IK3-1 / CABLES1 Antibody - IK3-1 / CABLES1 antibody Western Blot of Fetal Heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa516-565) Antibody
Human
WB
Unconjugated
100 µl/$424
IK3-1 / CABLES1 Antibody - IK3-1 / CABLES1 antibody Western Blot of Fetal Heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa516-565) (HRP) Antibody
Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
IK3-1 / CABLES1 Antibody - IK3-1 / CABLES1 antibody Western Blot of Fetal Heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa516-565) (Biotin) Antibody
Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
IK3-1 / CABLES1 Antibody - IK3-1 / CABLES1 antibody Western Blot of Fetal Heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IK3-1 / CABLES1 Rabbit anti-Human Polyclonal (aa516-565) (FITC) Antibody
Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
IK3-1 / CABLES1 Antibody - Western blot analysis of extracts of various cell lines, using CABLES1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
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IK3-1 / CABLES1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IK3-1 / CABLES1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
41.7 kDa
20 µg/$150
IK3-1 / CABLES1 Protein - 12.5% SDS-PAGE of human CABLES1 stained with Coomassie Blue
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Wheat Germ Extract
GST
68.3 kDa
10 µg/$479; 25 µg/$670
IK3-1 / CABLES1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
41.7 kDa
100 µg/$494
IK3-1 / CABLES1 Protein
Select
E. coli
His, N-Terminal
41.7 kDa
50 µg/$419
Viewing 1-23 of 23 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).