Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 6301 (7B10)] (IgG1) to Human IGFBP1
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [6301 (7B10)]
Protein A purified
Specificity and Use
IGFBP1 antibody was raised against human IGFBP-1.
Recognizes insulin-like growth factor 1, also known as somatomedin C. It shows minimal cross-reactivity with IGF-II, Proinsulin, MSF and Insulin. IGF-I is a secreted endocrine hormone that acts as the primary mediator for the effects of growth hormone.
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.