Human IGF1R / IGF1 Receptor
(tested or 100% immunogen sequence identity)
Also available Unconjugated
Protein G purified
- IHC - Paraffin
- Western blot
- Flow Cytometry (1:1)
- (applications tested for the base form of this product only)
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Recognizes human CD221, a 155kD receptor tyrosine kinase, also known as Insulin-like growth factor I receptor (IGF-I Receptor). CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. Recognizes an epitope in the alpha subunits of CD221, demonstrated by Western blotting. CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signalling proteins. Clone 1H7 is reported to partially block binding of IGF-I and IGF-II to CD221
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Lyophilized, PBS, 0.09% sodium azide, 1% BSA, 5% sucrose
100 tst 1 ml sterile distilled water
Store at 4°C. Do not freeze.
For research use only.
This antibody carries the LSBio 100% Guarantee.