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Anti-IGF1R / IGF1 Receptor Antibody (phospho-Tyr1316) LS-C7539

Ordering

Wt. Vol. Conc. Price
50 µg - 0.1 mg/ml $435
100 µg - - $680
Inquire for larger quantities

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Mouse Monoclonal (IgG1) to Human IGF1R / IGF1 Receptor
Human, Mouse
Western blot, ELISA
Unconjugated

Details

Human IGF1R / IGF1 Receptor
Mouse
Human, Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Gel filtration

Applications

Western blot (0.5 µg/ml), ELISA (0.1 µg/ml)

Specificity and Use

IGF1R / IGF1 Receptor antibody was raised against synthetic peptide corresponding to IGF1R (insulin-like growth factor 1 receptor) phosphorylated at Tyr1316.
pTyr1316
Recognizes human IGF1 Receptor phosphorylated at Tyr1316. Species cross-reactivity: Mouse.
Suitable for use in ELISA and Western Blot. ELISA: 0.1 ug/ml. Western Blot: 0.5 ug/ml for HRPO/ECL detection. Note: Recommended blocking buffer CPPT: 0.5% casein, 1% PEG 4000, 1% polyvinypyrrolidone (PVP), 0.1% Tween 20, 10 mM Tris/HCL, ph 7.4, 150 mM NaC. Positive control: I7661-18M1: Insulin-Like Growth Factor I Receptor, phosphorylated (Tyr1316) Positive Control (IGF1R). Supplied as a liquid cell lysate of 2x1E6 293 cells treated with insulin. Add 100 ul SDS-PAGE sample buffer and incubate at 90?C for 5 minutes. Aliquot and store at -20?C.

Packaging

PBS, pH 7.2, 0.1% sodium azide, PEG, sucrose, 40% glycerol.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About IGF1R / IGF1 Receptor

P08069 NM_000875 NP_000866.1

IGF1R Antibody, CD221 antigen Antibody, CD221 Antibody, IGF1 Receptor Antibody, IGFR Antibody, IGF-I receptor Antibody, Soluble IGF1R variant 1 Antibody, Soluble IGF1R variant 2 Antibody, Type 1 IGF receptor Antibody, IGFIR Antibody, JTK13 Antibody

Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell.

Requested From: United States
Date Requested: 9/26/2016

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