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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IGF1R / IGF1 Receptor Antibody (phospho‑Tyr1165/Tyr1166) LS‑C352358
IGF1 Receptor antibody LS-C352358 is an unconjugated rabbit polyclonal antibody to IGF1 Receptor (IGF1R) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C352358-100
100 µl (1 mg/ml)
$265

Popular IGF1R / IGF1 Receptor Products

Antibody
Species: Human, Rabbit
Applications: Immunoprecipitation, ELISA
IHC of paraffin-embedded human stomach mucosae showing membrane location using IGF1R antibody with DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
IHC of paraffin-embedded human prostate carcinoma using LS-C24709.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Anti-IGF1 Receptor antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2905 concentration 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Anti-IGF1 Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2613 concentration 10 ug/ml.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry

Product Description

IGF1R / IGF1 Receptor Antibody (phospho-Tyr1165/Tyr1166) for WB/Western LS-C352358

Specifications

Target
Human IGF1R / IGF1 Receptor
Synonyms
IGF1R, CD221 antigen, CD221, IGF1 Receptor, IGFR, IGF-I receptor, Soluble IGF1R variant 1, Soluble IGF1R variant 2, Type 1 IGF receptor, IGFIR, JTK13
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Chicken, Zebrafish (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-terminal region of human IGF1 Receptor.
Blocking Peptide
LS-E41591 - Lyophilized - 1 mg - $145.00
Immunizing peptide used to generate LS-C352358. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
pTyr1165/Tyr1166
Specificity
Recognizes endogenous levels of IGF1 Receptor (pY1165/Y1166) protein.
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only.
About IGF1R / IGF1 Receptor
Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. P08069 NM_000875 NP_000866.1


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Images

Western blot

Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.
Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.

Western blot

Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.
Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.

Western blot

Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.
Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.

Western blot

Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.
Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.

Requested From: United States
Date Requested: 10/21/2018

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