Human IGF1R / IGF1 Receptor
(tested or 100% immunogen sequence identity)
Also available conjugated with AP
Protein G purified
- Western blot
- (applications tested for the base form of this product only)
Synthetic peptide containing the amino acids (...D I pY E T...) in which pY corresponds to tyrosine 1131 of human IGF-1 receptor (accession # A25690, mature protein) and tyrosine 1185 of mature human Insulin Receptor (KLH coupled).
Recognizes phosphorylated human IGF-1R, Mr ~95kD. Also corresponds to tyrosine 1185 in human insulin receptor preprotein, containing a 27 amino acid signal peptide. Cross-reacts with phosphorylated insulin and PDGF receptors which contain the I Y E motif. Slight cross-reactivity detected with EGFR in A431 cells expressing very high levels of EGFR. Species cross-reactivity: mouse. Broad species cross-reactivity predicted based on sequence homology. The immunizing sequence is conserved from Drosophila to mammals.
PBS, pH 7.2. No preservative added.
For research use only.
This antibody carries the LSBio 100% Guarantee.