Human IGF1R / IGF1 Receptor
(tested or 100% immunogen sequence identity)
Also available conjugated with AP
Protein G purified
- Western blot
- (applications tested for the base form of this product only)
Synthetic peptide containing the amino acids (...D I pY E T...) in which pY corresponds to tyrosine 1131 of human IGF-1 receptor (accession # A25690, mature protein) and tyrosine 1185 of mature human Insulin Receptor (KLH coupled).
Recognizes phosphorylated human IGF-1R, Mr ~95kD. Also corresponds to tyrosine 1185 in human insulin receptor preprotein, containing a 27 amino acid signal peptide. Cross-reacts with phosphorylated insulin and PDGF receptors which contain the I Y E motif. Slight cross-reactivity detected with EGFR in A431 cells expressing very high levels of EGFR. Species cross-reactivity: mouse. Broad species cross-reactivity predicted based on sequence homology. The immunizing sequence is conserved from Drosophila to mammals.
PBS, pH 7.2, No preservatives added
For research use only.