Target
Human IGF1R / IGF1 Receptor
Synonyms
IGF1R | CD221 antigen | CD221 | IGF1 Receptor | IGFR | IGF-I receptor | Soluble IGF1R variant 1 | Soluble IGF1R variant 2 | Type 1 IGF receptor | IGFIR | JTK13
Reactivity
Human, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Immunogen
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA. Epitope: aa283-440 (exon 4-6). Cellular Localization: Cell membrane.
Specificity
Recognizes human Insulin-Like Growth Factor I Receptor, alpha (IGF1Ra) at 125kD. Species cross-reactivity: Weakly reacts with rabbit. Does not react with rat.
Applications
- Western blot
- Immunoprecipitation
- ELISA
Usage
Suitable for use in ELISA, Immunoprecipitation and as a weak IGF-like agonist in bioassays (Thymidine incorporation into DNA). Does not significantly Inhibit IGF-1 Binding. Not suitable for use in Western Blot. Immunoprecipitation: 2 ug/mg protein lysate using Protein G. ELISA: Capture Antibody. Positive control: Placenta or breast carcinoma.
Presentation
PBS, pH 7.4, 0.1% Sodium Azide, 40% Glycerol, 0.2% BSA
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About IGF1R / IGF1 Receptor