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Anti-IFNAR1 / IFNAR Antibody (aa3-240) LS-C185508

Catalog Size Price
LS-C185508-100 100 µl (0.48 mg/ml) Unavailable

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64 IFNAR1 / IFNAR Antibodies

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Western blot of immunoprecipitates from HEK 293 cells transfected with 1. Mock, 2. IFNAR1 WT, and 3. IFNAR1 S535A and S539A mutants showing specific immunolabeling of the -110k to -130k IFNAR1 WT. The immunolabeling is absent in IFNAR1 Ser5 35 and Se r539.
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IHC of paraffin-embedded human brain tissue, using Interferon-alpha/beta Receptor alpha chain (Ab-466) Antibody. The picture on the right is treated with the synthesized peptide.
Anti-IFNAR1 / IFNAR Antibody (aa162-188) LS-C165129
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Formalin-fixed and paraffin-embedded human hepatocarcinoma with IFNAR1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Anti-IFNAR1 / IFNAR Antibody (aa507-557) LS-C290931
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Detection of Human IFNAR1 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-IFNAR1 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

100% Guaranteed
Rabbit Polyclonal (IgG) to Human IFNAR1 / IFNAR
Human
Western blot
Unconjugated

Details

Human IFNAR1 / IFNAR
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (1:500 - 1:3000)

Specificity and Use

IFNAR1 / IFNAR antibody was raised against recombinant fragment corresponding to a region within amino acids 3 and 240 of interferon alpha Receptor 1 (SwissProt P17181).
aa3-240
Human IFNAR1 / IFNAR

Packaging

0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
For research use only.

About IFNAR1 / IFNAR

P17181 NM_000629 NP_000620.2

IFNAR1 Antibody, Alpha-type antiviral protein Antibody, Beta-type antiviral protein Antibody, CRF2-1 Antibody, IFN-alpha/beta receptor 1 Antibody, IFN-alpha-REC Antibody, IFN-R-1 Antibody, IFNAR Antibody, IFNBR Antibody, IFRC Antibody, Interferon-beta receptor 1 Antibody, Interferon-alpha receptor Antibody, Type I interferon receptor 1 Antibody

Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.

Western blot

Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.

Requested From: 
Date Requested: 4/25/2018

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