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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IFNAR1 / IFNAR Antibody (aa3‑240) LS‑C185508
IFNAR antibody LS-C185508 is an unconjugated rabbit polyclonal antibody to human IFNAR (IFNAR1). Validated for WB.
Catalog
Size
Price
LS-C185508-100
100 µl (0.48 mg/ml)
Unavailable

Popular IFNAR1 / IFNAR Products

Western blot of immunoprecipitates from HEK 293 cells transfected with 1. Mock, 2. IFNAR1 WT, and 3. IFNAR1 S535A and S539A mutants showing specific immunolabeling of the -110k to -130k IFNAR1 WT. The immunolabeling is absent in IFNAR1 Ser5 35 and Se r539.
Species: Human, Mouse, Rat, Bovine, Dog
Applications: IHC, Western blot
IHC of paraffin-embedded human brain tissue, using Interferon-alpha/beta Receptor alpha chain (Ab-466) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Formalin-fixed and paraffin-embedded human hepatocarcinoma with IFNAR1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Antibody
Species: Human
Applications: Flow Cytometry
Detection of Human IFNAR1 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-IFNAR1 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Species: Human
Applications: Western blot, Immunoprecipitation

Product Description

IFNAR antibody LS-C185508 is an unconjugated rabbit polyclonal antibody to human IFNAR (IFNAR1). Validated for WB.
About IFNAR1 / IFNAR
Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway. P17181 NM_000629 NP_000620.2

IFNAR1 Antibody, Alpha-type antiviral protein Antibody, Beta-type antiviral protein Antibody, CRF2-1 Antibody, IFN-alpha/beta receptor 1 Antibody, IFN-alpha-REC Antibody, IFN-R-1 Antibody, IFNAR Antibody, IFNBR Antibody, IFRC Antibody, Interferon-beta receptor 1 Antibody, Interferon-alpha receptor Antibody, Type I interferon receptor 1 Antibody


Specifications

Target
Human IFNAR1 / IFNAR
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:3000)
Immunogen
IFNAR1 / IFNAR antibody was raised against recombinant fragment corresponding to a region within amino acids 3 and 240 of interferon alpha Receptor 1 (SwissProt P17181).
Epitope
aa3-240
Specificity
Human IFNAR1 / IFNAR
Presentation
0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Storage
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.

Western blot

Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.

Western blot

Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.

Western blot

Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. IFNAR1 / IFNAR antibody diluted at 1:1000.


Requested From: 
Date Requested: 6/18/2018

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