IFIT1 / ISG56

interferon-induced protein with tetratricopeptide repeats 1

Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.

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Products

Antibodies (32)

ELISA Kits (4)

Proteins (4)

Type

Custom (1)

Over-Expression Lysate (1)

Primary (32)

Recombinant (3)

Sandwich (3)

Target

IFIT1 / ISG56 (40)

Reactivity

Human (35)

Mouse (3)

Rat (2)

Chimpanzee (6)

Gibbon (3)

Monkey (1)

Orangutan (3)

Application

IHC (6)

IHC-P (1)

WB (28)

Flo (2)

ELISA (7)

IF (4)

IP (1)

Peptide-ELISA (2)

Host

rabbit (29)

mouse (3)

Isotype

IgG (17)

IgG1 (2)

Clonality

monoclonal mc (2)

polyclonal pc (30)

Clone

OTI3G8 (2)

Format

96-Well Strip Plate (4)

APC Conjugated (1)

Biotin Conjugated (5)

Carrier-free (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (1)

Unconjugated (15)

Epitope

C-Terminus (5)

aa100-148 (4)

aa270-319 (4)

10-90 aa, N-terminal (1)

aa41-90 (1)

Publications

No (40)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (3)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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IFIT1 / ISG56 Antibody (clone OTI3G8) LS-C175767

Antibody:

IFIT1 / ISG56 Mouse anti-Human Monoclonal (OTI3G8) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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IFIT1 / ISG56 Antibody (clone OTI3G8, Carrier-free) LS-C784550

Antibody:

IFIT1 / ISG56 Mouse anti-Human Monoclonal (Carrier-free) (OTI3G8) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$512

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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Human IFIT1 / ISG56 (Sandwich ELISA) ELISA Kit - LS-F13244

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Human IFIT1 / ISG56 (Sandwich ELISA) ELISA Kit - LS-F52075

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Human IFIT1 / ISG56 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66083

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.2 kDa

Price:

20 µg/$1,107

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IFIT1 / ISG56 Antibody (C-Terminus) LS-C345670

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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IFIT1 / ISG56 Antibody (C-Terminus, FITC) LS-C480362

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• FITC

• Unconjugated
• FITC

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IFIT1 / ISG56 Antibody (aa100-148) LS-C187049

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (aa100-148) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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IFIT1 / ISG56 Antibody LS-C499106

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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IFIT1 / ISG56 Antibody (HRP) LS-C499093

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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IFIT1 / ISG56 Antibody (Biotin) LS-C499112

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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IFIT1 / ISG56 Antibody (FITC) LS-C499127

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IFIT1 / ISG56 Antibody LS-C666313

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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IFIT1 / ISG56 Antibody (10-90 aa, N-terminal) LS-C384052

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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IFIT1 / ISG56 Antibody LS-C808693

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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IFIT1 / ISG56 Antibody (C-Terminus) LS-C144905

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

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IFIT1 / ISG56 Antibody LS-C823565

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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IFIT1 / ISG56 Antibody LS-C310697

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$749

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IFIT1 / ISG56 Antibody (aa41-90) LS-C119527

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (aa41-90) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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IFIT1 / ISG56 Antibody LS-C310699

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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IFIT1 / ISG56 Antibody (Biotin) LS-C522508

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

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IFIT1 / ISG56 Antibody (PE) LS-C650750

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

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IFIT1 / ISG56 Antibody (APC) LS-C514292

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

• Unconjugated
• Biotin
• PE
• APC

• Unconjugated
• Biotin
• PE
• More...
  • APC

Select

IFIT1 / ISG56 Antibody (aa270-319) LS-C151454

Antibody:

IFIT1 / ISG56 Rabbit anti-Human Polyclonal (aa270-319) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

IFIT1 / ISG56 Antibody LS-C308387

Antibody:

IFIT1 / ISG56 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

Viewing 1-25 of 40 product results

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