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| Catalog Number | Size | Price |
|---|---|---|
| LS-C153780-100 | 100 µg (1.09 mg/ml) | $574 |
Monoclonal Mouse anti‑Human IDO1 / IDO Antibody (clone 10.1, IHC, IF, WB) LS‑C153780
Monoclonal Mouse anti‑Human IDO1 / IDO Antibody (clone 10.1, IHC, IF, WB) LS‑C153780
Note: This antibody replaces LS-C45686
Antibody:
IDO1 / IDO Mouse anti-Human Monoclonal (10.1) Antibody
Application:
IHC, IF, WB, IP, ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
IDO1 / IDO Mouse anti-Human Monoclonal (10.1) Antibody
Application:
IHC, IF, WB, IP, ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
IDO antibody LS-C153780 is an unconjugated mouse monoclonal antibody to IDO (IDO1) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC, IP and WB. Cited in 5 publications.
Target
Human IDO1 / IDO
Synonyms
IDO1 | IDO | Indole 2,3-dioxygenase | Indolamine 2,3 dioxygenase | IDO-1 | INDO | Indoleamine 2,3-dioxygenase | Indoleamine 2,3-dioxygenase 1
Host
Mouse
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG3
Monoclonal
Clone
10.1
Conjugations
Unconjugated
Purification
Protein G affinity chromatography
Modifications
Unmodified
Immunogen
Anti-IDO1 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with fragment of recombinant human and mouse IDO1 protein followed by hybridoma development.
Specificity
This antibody is specific for human and mouse IDO1 protein. A BLAST analysis was used to suggest cross-reactivity with IDO1 from human and mouse sources based on 100% homology with the immunizing sequence. Cross-reactivity with IDO1 from other sources has not been determined.
Applications
- IHC (1:100 - 1:500)
- Immunofluorescence (1:50 - 1:100)
- Western blot (1:500 - 1:1500)
- Immunoprecipitation
- ELISA (1:5000 - 1:50000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Anti-IDO1 antibody has been tested for use in ELISA, Western Blot, IP and IHC. Specific conditions for reactivity should be optimized by the end user.
Presentation
0.02 M Potassium Phosphate, pH 7.2, 0.15 M NaCl, 0.01% Sodium Azide
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About IDO1 / IDO
LSBio Ratings
IDO1 / IDO Antibody (clone 10.1) for IHC, IF/Immunofluorescence, WB/Western, IP, ELISA LS-C153780 has an LSBio Rating of
Publications (4.4)
Learn more about The LSBio Ratings Algorithm
Publications (5)
Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. Zhu L, Ji F, Wang Y, Zhang Y, Liu Q, Zhang JZ, Matsushima K, Cao Q, Zhang Y. Journal of immunology (Baltimore, Md. : 1950). 2006 177:8226-33.
Imaging correlates of differential expression of indoleamine 2,3-dioxygenase in human brain tumors. Batista CE, Juhsz C, Muzik O, Kupsky WJ, Barger G, Chugani HT, Mittal S, Sood S, Chakraborty PK, Chugani DC. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 11:460-6.
Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions. Gulati N, Suárez-Fariñas M, Correa da Rosa J, Krueger JG. F1000Research. 2015 4:149. (IHC; Human)
Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment. Schafer CC, Wang Y, Hough KP, Sawant A, Grant SC, Thannickal VJ, Zmijewski J, Ponnazhagan S, Deshane JS. Oncotarget. 2016 November;7:75407-75424.
IL-32 induces indoleamine 2,3-dioxygenase+CD1c+ dendritic cells and indoleamine 2,3-dioxygenase+CD163+ macrophages: Relevance to mycosis fungoides progression. Ohmatsu H, Humme D, Gonzalez J, Gulati N, Möbs M, Sterry W, Krueger JG. Oncoimmunology. 2016 May;6:e1181237.
Customer Reviews (0)
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Species:
Human, Monkey, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Mouse
Applications:
IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/23/2024
Date Requested: 4/23/2024
