Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IHC - Frozen
Specificity and Use
ID2 antibody was raised against peptide sequence from the C-terminal region of Id2.
Recognizes human Id2. Expected Staining Pattern: Nucleus.
Suitable for use in Immunohistochemistry (FFPE or frozen). Immunohistochemistry: Requires EDTA, pH 8.0. Heat Induced. Epitope Retrieval (HIER). Positive control: Selected neuroblastoma or normal testis.
PBS, pH 7.4, 1% BSA, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
ID2 Antibody, BHLHb26 Antibody, Cell growth-inhibiting gene 8 Antibody, ID2H Antibody, Inhibitor of differentiation 2 Antibody, GIG8 Antibody, Helix-loop-helix protein ID2 Antibody, ID2A Antibody, Inhibitor of DNA binding 2 Antibody
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation.