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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ICOS / CD278 Antibody (clone ANC6C6‑A3, FITC) LS‑C134609
CD278 antibody LS-C134609 is an FITC-conjugated mouse monoclonal antibody to human CD278 (ICOS). Validated for ELISA, Flow and Func.
Catalog
Size
Price
LS-C134609-120
120 tst
Unavailable

Popular ICOS / CD278 Products

Surface staining of CD3 + CD28 stimulated human PBMC with anti-human ICOS (ISA-3) PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.
Species: Human
Applications: IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Staining of 3-day unstimulated (left) and 3-day anti-CD3/CD28 stimulated (right) human peripheral blood cells with PE Mouse IgG1, K Isotype Control (blue histogram) or PE anti-human ICOS (purple histogram). Cell in the lymphocytes gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry
Anti-ICOS antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4395 concentration 3.75 ug/ml.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Peptide Enzyme-Linked Immunosorbent Assay
Flow cytometry of ICOS antibody
Species: Human
Applications: Flow Cytometry, ELISA, Functional Assay
Flow cytometry of ICOS antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry, ELISA, Functional Assay

Product Description

CD278 antibody LS-C134609 is an FITC-conjugated mouse monoclonal antibody to human CD278 (ICOS). Validated for ELISA, Flow and Func.
About ICOS / CD278
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Q9Y6W8 AJ277832 CAC06612.1

ICOS Antibody, AILIM Antibody, CD278 Antibody, CVID1 Antibody, Inducible costimulator Antibody, Inducible T-cell co-stimulator Antibody, CD278 antigen Antibody, Inducible T-cell costimulator Antibody


Specifications

Target
Human ICOS / CD278
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [ANC6C6-A3]
Conjugations
Fluorescein. Also available Unconjugated or conjugated with Biotin, RPE, APC.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Flow Cytometry
  • ELISA
  • Functional Assay
  • (applications tested for the base form of this product only)
Immunogen
ICOS / CD278 antibody was raised against human HPB-MLT cells, recombinant human CD278(ICOS)-muIg.
Specificity
Recombinant and cell surface CD278 (ICOS).
Usage
Flow Cytometry: 1:50 (or use 1.6?l of concentrated stock per 5 x 10^5 cell test), Function: Blocks binding of Recombinant CD275-muIg to CD278. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5% Glycerol, 0.2% BSA, 0.04% sodium azide
Storage
Store at 4°C. Do not freeze. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Flow Cytometry

Flow cytometry of ICOS antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of ICOS antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of ICOS antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of ICOS antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of ICOS antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of ICOS antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of ICOS antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of ICOS antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/23/2018

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