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| Catalog Number | Size | Price |
|---|---|---|
| LS-B4395-50 | 50 µg (0.5 mg/ml) | $485 |
1 of 2
2 of 2
IHC‑plus™ Polyclonal Goat anti‑Human ICOS / CD278 Antibody (aa57‑71, IHC) LS‑B4395
IHC‑plus™ Polyclonal Goat anti‑Human ICOS / CD278 Antibody (aa57‑71, IHC) LS‑B4395
Note: This antibody replaces LS-C108141
Antibody:
ICOS / CD278 Goat anti-Human Polyclonal (aa57-71) Antibody
Application:
IHC, IHC-P, Peptide-ELISA
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
ICOS / CD278 Goat anti-Human Polyclonal (aa57-71) Antibody
Application:
IHC, IHC-P, Peptide-ELISA
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
CD278 antibody LS-B4395 is an unconjugated goat polyclonal antibody to CD278 (ICOS) (aa57-71) from human. It is reactive with human and monkey. Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
Target
Human ICOS / CD278
Synonyms
ICOS | AILIM | CD278 | CVID1 | Inducible costimulator | Inducible T-cell co-stimulator | CD278 antigen | Inducible T-cell costimulator
Host
Goat
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
Peptide with sequence KGGQILCDLTKTKGS, from the internal region of the protein sequence according to NP_036224.1.
Epitope
aa57-71
Specificity
Human ICOS.
Applications
- IHC
- IHC - Paraffin (3.75 µg/ml)
- Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western Blot: Preliminary experiments gave an approx 13kD band in Human Peripheral Blood Lymphocyte lysates after 0.01 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 22.6kD according to NP_036224.1. The 13kD band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ICOS / CD278
Validation
Anti-ICOS antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-ICOS antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-ICOS antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-ICOS antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ ICOS / CD278 Antibody (aa57-71) for IHC LS-B4395 has an LSBio Rating of
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
Flow Cytometry, ELISA, Functional Assay
Species:
Human
Applications:
Flow Cytometry, ELISA, Functional Assay
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
IHC, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
