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Anti-ICOS / CD278 Antibody (aa171-186) IHC-plus™ LS-B814

Note: This antibody replaces LS-C3065

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml Unavailable

Most Popular ICOS / CD278 Antibodies

Anti-ICOS / CD278 Antibody (clone ISA-3) LS-C106787
Mouse Monoclonal [clone ISA-3] (IgG1,k) to Human ICOS / CD278
Human
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated
Flow Cytometry Image
Anti-ICOS / CD278 Antibody (clone ISA-3, PE) LS-C107343
Mouse Monoclonal [clone ISA-3] (IgG1,k) to Human ICOS / CD278
Human
Flow Cytometry
PE Conjugated
Flow Cytometry Image
Anti-ICOS / CD278 Antibody (aa57-71) IHC-plus™ LS-B4395
Goat Polyclonal to Human ICOS / CD278
Human, Monkey
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image

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Rabbit Polyclonal to Human ICOS / CD278
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human ICOS / CD278
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • ELISA (1:1000)

Specificity and Use

ICOS / CD278 antibody was raised against synthetic peptide from human ICOS.
aa171-186
Amino acids 171 to 186 of human ICOS
Immunohistochemistry: LS-B814 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B814 was determined to be 10 ug/ml.

Packaging

PBS with 0.09% Sodium Azide
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About ICOS / CD278

Q9Y6W8 AJ277832 CAC06612.1

ICOS Antibody, AILIM Antibody, CD278 Antibody, CVID1 Antibody, Inducible costimulator Antibody, Inducible T-cell co-stimulator Antibody, CD278 antigen Antibody, Inducible T-cell costimulator Antibody

Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10.

Immunohistochemistry

Immunohistochemistry
Anti-ICOS antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B814 concentration 10 ug/ml.
 

Requested From: 
Date Requested: 3/30/2017

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