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Anti-ICAM3 / CD50 Antibody (RPE) LS-C44738

Note: This antibody replaces LS-C57909

Ordering

Wt. Vol. Conc. Price
- 100 tst - $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ICAM3 / CD50 Antibodies

Anti-ICAM3 / CD50 Antibody (clone 2F8) IHC-plus™ LS-B5955
Mouse Monoclonal [clone 2F8] (IgG2b,k) to Human ICAM3 / CD50
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-ICAM3 / CD50 Antibody LS-C485001
Mouse Monoclonal to Human ICAM3 / CD50
Human
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human ICAM3 / CD50
Human
Flow Cytometry
RPE Conjugated

Details

Human ICAM3 / CD50
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
R. Phycoerythrin
Protein G purified
Unmodified

Applications

Flow Cytometry (1:1 - 1:5)

Specificity and Use

ICAM3 / CD50 antibody was raised against human granulocytes.
Recognizes the human CD50 cell surface glycoprotein, a 110kD molecule also known as ICAM-3. CD50 is a type I transmembrane glycoprotein, containing five immunoglobulin-like C2-type domains, and is a ligand for LFA-1. CD50 is expressed by a wide range of leucocytes. It plays a role in leucocyte adhesion and also acts as a signaling and costimulatory molecule on T lymphocytes. Recognizes an epitope in the D2 domain of human CD50. This clone is reported to partially inhibit CD43 induced apoptosis of TF-1 cells.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
100 tst Distilled Water.
For research use only.

About ICAM3 / CD50

P32942 NM_002162 NP_002153.2

ICAM3 Antibody, CD50 Antibody, CDW50 Antibody, ICAM-R Antibody, CD50 antigen Antibody, ICAM-3 Antibody

ICAM3 / CD50 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.

Requested From: United States
Date Requested: 12/4/2016

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