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IBSP / Bone Sialoprotein

integrin-binding sialoprotein

IBSP / Bone Sialoprotein is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Gene Name: integrin-binding sialoprotein
Synonyms: IBSP, Bone Sialoprotein, Bone sialoprotein II, BSP, BSP II, Cell-binding sialoprotein, BNSP, Bone Sialprotein II, Integrin-binding sialoprotein, Bone sialoprotein 2, BSP-II, SP-II
Target Sequences: NM_004967 NP_004958.2 P21815

Publications (2)

1
BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts. Yuhei Yahiro #, Shingo Maeda #, Masato Morikawa, Daizo Koinuma, Go Jokoji, Toshiro Ijuin, Setsuro Komiya, Ryoichiro Kageyama, Kohei Miyazono, Noboru Taniguchi. Bone research. 2020 September;8:32. [Full Text Article] [PubMed:32923015] [PMC:PMC7463266] Related Antibodies: LS-C190916.
2
Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation. Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S. The Journal of biological chemistry. 2014 Apr;289:9865-79. [Full Text Article] [PubMed:24563464] [PMC:PMC3975031] Related Antibodies: LS-C190916.

☰ Filters
Antibodies (35)
ELISA Kits (17)
Proteins (9)
Competitive EIA (1)
Custom (5)
Over-Expression Lysate (2)
Primary (35)
Recombinant (7)
Sandwich (9)
Sandwich CLIA (2)
IBSP / Bone Sialoprotein (61)
Human (38)
Mouse (14)
Rat (13)
Chicken (1)
Dog (2)
Gibbon (3)
Monkey (1)
Pig (1)
IHC (9)
IHC-Fr (1)
IHC-P (7)
WB (28)
ELISA (23)
ICC (7)
IF (1)
IP (1)
Peptide-ELISA (1)
RIA (3)
rabbit (30)
mouse (2)
goat (2)
rat (1)
Product Group
IHCPlus (1)
IgG (20)
IgG1 (3)
monoclonal mc (3)
polyclonal pc (32)
ID1.2 (1)
IDBSP5 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (3)
96-Well Strip Plate (13)
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Azide-free (1)
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HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (27)
aa70-99 (7)
aa108-157 (4)
aa262-279 (2)
C-Terminus (1)
N-Terminus (1)
aa108-122 (1)
aa17-34 (1)
aa201-211 (1)
aa284-295 (1)
aa305-324 (1)
aa39-47 (1)
No (60)
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6His-SUMO, N-terminus (1)
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Human (6)
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Low endotoxin level (3)
IBSP / Bone Sialoprotein Antibody - IBSP / Bone Sialoprotein antibody. IHC(P): Human Osteosarcoma Tissue.
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal (aa17-34) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
100 µl/$688
Select
IBSP / Bone Sialoprotein Mouse anti-Human Monoclonal (ID1.2) Antibody
Human
ELISA, ICC, IHC, IHC-Fr, IHC-P, RIA, WB
Unconjugated
10 µg/$483; 100 µg/$973
Select
IBSP / Bone Sialoprotein Mouse anti-Human Monoclonal (C-Terminus) Antibody
Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$848
IBSP / Bone Sialoprotein Antibody - IBSP / Bone Sialoprotein antibody. IHC(P): Rat Liver Tissue.
Select
IBSP / Bone Sialoprotein Rabbit anti-Mouse Polyclonal (aa305-324) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
20 µl/$626; 100 µl/$969
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IBSP / Bone Sialoprotein Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P
Unconjugated
60 µl/$460
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC, RIA, WB
Unconjugated
100 µl/$826
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.63 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IBSP / Bone Sialoprotein ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal (aa108-122) Antibody
Human
ELISA, ICC, WB
Unconjugated
20 µl/$508; 100 µl/$996
IBSP / Bone Sialoprotein Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using IBSP Polyclonal Antibody at dilution of 1:30(×200)
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal (aa39-47) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
20 µl/$544; 100 µl/$1,079
IBSP / Bone Sialoprotein Antibody - Western blot analysis of Bone Sialoprotein using K562 whole lysates.
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal (aa262-279) Antibody
Dog, Human
ELISA, ICC
Unconjugated
20 µl/$390
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal (aa201-211) Antibody
Human
ELISA, ICC
Unconjugated
20 µl/$508; 100 µl/$996
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal (aa262-279) Antibody
Dog, Human
ELISA, ICC
Unconjugated
20 µl/$508; 100 µl/$996
Select
IBSP / Bone Sialoprotein Rat anti-Human Monoclonal (IDBSP5) Antibody
Human
ELISA, WB
Unconjugated
10 µg/$508; 100 µg/$934
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal (aa70-99) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
IBSP / Bone Sialoprotein Rabbit anti-Human Polyclonal (aa70-99) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Viewing 1-25 of 61 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).