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Anti-IAPP / Amylin Antibody (Internal) LS-C20521

Catalog Size Price
LS-C20521-50 50 µl Unavailable

Related Products

56 IAPP / Amylin Antibodies

Most Popular IAPP / Amylin Antibodies

Anti-IAPP / Amylin Antibody LS-C20520
Rabbit Polyclonal (IgG) to Human IAPP / Amylin
Human
Western blot, ELISA
Unconjugated
Anti-IAPP / Amylin Antibody (Internal) LS-C20521
Rabbit Polyclonal (IgG) to Human IAPP / Amylin
Human
Western blot, ELISA
Unconjugated
Anti-IAPP / Amylin Antibody (Internal) LS-C20522
Rabbit Polyclonal (IgG) to Human IAPP / Amylin
Human
Western blot, ELISA
Unconjugated
Anti-IAPP / Amylin Antibody (clone R10/99) IHC-plus™ LS-B35
Mouse Monoclonal [clone R10/99] (IgG1) to Human IAPP / Amylin
Human
IHC, IHC - Paraffin, IHC - Frozen, Immunofluorescence
Unconjugated
Anti-Amylin antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B35 concentration 5 ug/ml.
Anti-IAPP / Amylin Antibody (N-Terminus) IHC-plus™ LS-B2785
Rabbit Polyclonal to Human IAPP / Amylin
Human
IHC, IHC - Paraffin
Unconjugated
Anti-Amylin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2785 concentration 10 ug/ml.

100% Guaranteed Publications (2)
Rabbit Polyclonal (IgG) to Human IAPP / Amylin
Human
Western blot, ELISA
Unconjugated

Details

Human IAPP / Amylin
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:50000)

Specificity and Use

IAPP / Amylin antibody was raised against kLH-conjugated peptide mapping to amino acids 18-30 (HSSNNFGAILSST) of human IAPP, UniProt accession #P10997
Internal
Recognizes human amylin. No significant sequence homology with other calcitonin family of peptides. Species sequence homology (< 50%): Mouse, rat
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000. ELISA: 1:10000-1:50000. Coat ELISA plates at 1 ug/ml with Control Peptide.

Packaging

PBS, 0.05% sodium azide
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

Publications (2)

1
Amylin deposition in the brain: A second amyloid in Alzheimer disease?. Jackson K, Barisone GA, Diaz E, Jin LW, DeCarli C, Despa F. Annals of neurology. 2013 Oct;74:517-26. [Full Text Article] [PubMed:23794448] [PMC:PMC3818462]
2
Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. Despa S, Sharma S, Harris TR, Dong H, Li N, Chiamvimonvat N, Taegtmeyer H, Margulies KB, Hammock BD, Despa F. Journal of the American Heart Association. 2014 3: (WB; Human) [Full Text Article] [PubMed:25146704] [PMC:PMC4310392]

About IAPP / Amylin

P10997 NM_000415 NP_000406.1

IAPP Antibody, Diabetes-associated peptide Antibody, Islet amyloid polypeptide Antibody, AMYLIN Antibody, IAP Antibody, Insulinoma amyloid peptide Antibody

IAPP / Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. This protein also exhibits an bactericidal, antimicrobial activity.

Requested From: 
Date Requested: 4/23/2018

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