Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
IHC - Paraffin (3.75 - 7.5 µg/ml)
Specificity and Use
HYAL2 antibody was raised against synthetic peptide RAGPGPTVTLAC from the N-terminus of human HYAL2 (NP_003764.3). Percent identity by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey, Marmoset (91%); Horse, Pufferfish (82%).
LS-E25820 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B5114. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human HYAL2. Reported variants NP_003764 and NP_149348 represent identical proteins.
HYAL2 is a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation.