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HUPF2 / UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.
| Gene Name: | UPF2 regulator of nonsense transcripts homolog (yeast) |
| Synonyms: | UPF2, DKFZP434D222, KIAA1408, RENT2, Smg-3, Yeast Upf2p homolog, HUPF2 |
| Target Sequences: | NM_015542 NP_056357.1 Q9HAU5 |
Publications (1)
1
Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness. Nguyen A, Yoshida M, Goodarzi H, Tavazoie SF. Nature communications. 2016 7:11246. (WB; Human)
[Full Text Article]
[PubMed:27138336]
[PMC:PMC4857405]
Related Antibodies: LS-C160443.
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(17)
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HUPF2 / UPF2
(22)
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(16)
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(10)
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(17)
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(2)
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(2)
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(1)
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(9)
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(7)
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(4)
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(1)
aa1250-1262
(1)
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(21)
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(5)
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(3)
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293T Cells
(2)
HEK 293 Cells
(3)
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa630-656) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
HUPF2 / UPF2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
HUPF2 / UPF2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa630-656) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa630-656) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa630-656) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa630-656) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa630-656) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa630-656) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
HUPF2 / UPF2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
HUPF2 / UPF2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa51-100) Antibody
Human
WB
Unconjugated
100 µl/$424
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa51-100) (HRP) Antibody
Mouse, Rat, Horse, Gibbon, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa51-100) (Biotin) Antibody
Mouse, Rat, Horse, Gibbon, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
HUPF2 / UPF2 Rabbit anti-Human Polyclonal (aa51-100) (FITC) Antibody
Mouse, Rat, Horse, Gibbon, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
HUPF2 / UPF2 Goat anti-Human Polyclonal (aa1250-1262) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Hamster, Pig, Horse, Bat, Human, Monkey
Peptide-ELISA
Unconjugated
100 µg/$384
HEK 293 Cells
Myc-DDK (Flag)
147.6 kDa
20 µg/$1,107
293T Cells
Myc-DDK (Flag)
147.6 kDa
20 µg/$215
293T Cells
Myc-DDK (Flag)
147.6 kDa
20 µg/$215
HEK 293 Cells
Myc-DDK (Flag)
147.6 kDa
100 µg/$710
HEK 293 Cells
Myc-DDK (Flag)
147.6 kDa
100 µg/$710
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