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| Catalog Number | Size | Price |
|---|---|---|
| LS-A6922-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human HUNK / B19 Antibody (Internal, IHC) LS‑A6922
PathPlus™ Polyclonal Rabbit anti‑Human HUNK / B19 Antibody (Internal, IHC) LS‑A6922
Antibody:
HUNK / B19 Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
HUNK / B19 Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
HUNK is an AMPK/SNF1 -type protein kinase with a domain homologous to SNF1, a protein involved in the response to nutritional stress in yeast. HUNK negatively regulates intestinal cell proliferation, and is thought to play a role in aberrant WNT signaling activation and tumor cell growth in APC-mutated colorectal neoplasia. HUNK also plays a role in vesicular transport, and likely controls endocytosis through interaction with rabaptin-5 protein. It can induce changes in mammary glands during pregnancy.
References: BMC Cancer 15, 110 (2015) doi:10.1186/s12885-015-1087-2
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from internal region of human HUNK. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%).
Epitope
Internal
Specificity
Human HUNK. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (8 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HUNK / B19
Validation
Breast carcinoma
Breast carcinoma
Colon, Carcinoma
Colon, Carcinoma
Breast, Carcinoma
Breast, Carcinoma
Anti-HUNK antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HUNK antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HUNK / B19 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HUNK / B19 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ HUNK / B19 Antibody (Internal) for IHC LS-A6922 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Rabbit, Chicken
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Rabbit, Chicken
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Monkey, Bovine
Applications:
IHC, IHC - Paraffin, ELISA
Reactivity:
Human
Range:
40-10000 pg/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
